STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
R02F2.7Uncharacterized protein. (693 aa)    
Predicted Functional Partners:
K04C2.2
Uncharacterized protein.
   
   0.674
nsun-5
SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
   
    0.536
Y53C12B.1
WD_REPEATS_REGION domain-containing protein.
   
    0.513
Y45F10D.7
Uncharacterized protein.
   
    0.502
rbd-1
RBD (RNA binding domain) protein.
   
    0.473
nath-10
RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.
   
    0.468
rrp-1
Ribosomal RNA processing protein 1 homolog; May be involved in the generation of 28S rRNA. Belongs to the RRP1 family.
   
    0.459
pro-1
Pre-rRNA-processing protein pro-1; Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit (By similarity). Required for processing ITS2 sequences from rRNA intermediates during 26S rRNA maturation. Required in the soma to promote normal proliferation and prevent germline tumor formation. Belongs to the WD repeat IPI3/WDR18 family.
   
    0.445
rpoa-1
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
    0.428
T20B12.3
Uncharacterized protein T20B12.3; Belongs to the CBF/MAK21 family.
   
    0.422
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.