STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
msp-32Major sperm protein 32; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (119 aa)    
Predicted Functional Partners:
msp-59
Major sperm protein 19/31/40/45/50/51/53/59/61/65/81/113/142.
   
   
0.999
msp-142
Major sperm protein 19/31/40/45/50/51/53/59/61/65/81/113/142.
   
   
0.916
vms-1
Protein vms-1; Involved in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway. Component of an evolutionarily conserved system for ubiquitin-mediated mitochondria-associated protein degradation (MAD) (By similarity). Dispensable for viability and growth but is required for protection against oxidative stress and for wild- type life span.
    
 
 0.861
msp-63
Major sperm protein 63; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.
   
   
0.846
ttm-2
Protein ttm-2; Involved in resistance to B.thuringiensis pore-forming toxin Cry5B downstream of the sek-1 and pmk-1 MAPK kinase pathway.
      
 0.697
msp-78
Major sperm protein 78; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.
   
   
0.593
msp-49
Major sperm protein 49; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.
   
   
0.592
F58A6.9
Major Sperm Protein.
   
   
0.592
msp-76
Major sperm protein 10/36/56/76.
   
   
0.592
msp-51
Major sperm protein 19/31/40/45/50/51/53/59/61/65/81/113/142.
   
   
0.592
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.