node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
R05H5.3 | T19H12.2 | R05H5.3.1 | T19H12.2.1 | Thioredoxin domain-containing protein. | Acidic leucine-rich nuclear phosphoprotein 32-related protein 2; Belongs to the ANP32 family. | 0.532 |
R05H5.3 | Y73B6BL.12 | R05H5.3.1 | Y73B6BL.12.1 | Thioredoxin domain-containing protein. | Thioredoxin; Belongs to the thioredoxin family. | 0.763 |
R05H5.3 | cdk-1 | R05H5.3.1 | T05G5.3.2 | Thioredoxin domain-containing protein. | Cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II (By similarity). | 0.441 |
R05H5.3 | ify-1 | R05H5.3.1 | C27A2.3.2 | Thioredoxin domain-containing protein. | Securin-like protein; Acts as a chaperone and as an inhibitor for separase sep-1. Plays an essential role in maintaining chromosome cohesion prior to meiotic and mitotic anaphase, in cytokinesis and in organizing the spindle and the centrosome. Ubiquitination-dependent degradation at the onset of anaphase is likely to activate sep-1 resulting in the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes. Also required for cortical granule exocytosis. | 0.441 |
R05H5.3 | nasp-2 | R05H5.3.1 | C50B6.2.1 | Thioredoxin domain-containing protein. | SHNi-TPR domain-containing protein. | 0.538 |
R05H5.3 | pcn-1 | R05H5.3.1 | W03D2.4.1 | Thioredoxin domain-containing protein. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.538 |
R05H5.3 | prx-3 | R05H5.3.1 | C15H9.8a.1 | Thioredoxin domain-containing protein. | PeRoXisome assembly factor. | 0.459 |
R05H5.3 | rbx-1 | R05H5.3.1 | ZK287.5.2 | Thioredoxin domain-containing protein. | RING-box protein 1; Component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate (By similarity). Essential for meiosis, mitotic chromosomal condensation and cytokinesis. Involved in histone H3 phosphorylation. | 0.507 |
R05H5.3 | trx-2 | R05H5.3.1 | B0024.9a.2 | Thioredoxin domain-containing protein. | Probable thioredoxin-2; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. | 0.432 |
R05H5.3 | trx-4 | R05H5.3.1 | Y44E3A.3.1 | Thioredoxin domain-containing protein. | Thioredoxin; Belongs to the thioredoxin family. | 0.836 |
T19H12.2 | R05H5.3 | T19H12.2.1 | R05H5.3.1 | Acidic leucine-rich nuclear phosphoprotein 32-related protein 2; Belongs to the ANP32 family. | Thioredoxin domain-containing protein. | 0.532 |
T19H12.2 | ify-1 | T19H12.2.1 | C27A2.3.2 | Acidic leucine-rich nuclear phosphoprotein 32-related protein 2; Belongs to the ANP32 family. | Securin-like protein; Acts as a chaperone and as an inhibitor for separase sep-1. Plays an essential role in maintaining chromosome cohesion prior to meiotic and mitotic anaphase, in cytokinesis and in organizing the spindle and the centrosome. Ubiquitination-dependent degradation at the onset of anaphase is likely to activate sep-1 resulting in the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes. Also required for cortical granule exocytosis. | 0.539 |
T19H12.2 | nasp-2 | T19H12.2.1 | C50B6.2.1 | Acidic leucine-rich nuclear phosphoprotein 32-related protein 2; Belongs to the ANP32 family. | SHNi-TPR domain-containing protein. | 0.731 |
T19H12.2 | pcn-1 | T19H12.2.1 | W03D2.4.1 | Acidic leucine-rich nuclear phosphoprotein 32-related protein 2; Belongs to the ANP32 family. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.897 |
Y73B6BL.12 | R05H5.3 | Y73B6BL.12.1 | R05H5.3.1 | Thioredoxin; Belongs to the thioredoxin family. | Thioredoxin domain-containing protein. | 0.763 |
Y73B6BL.12 | trx-2 | Y73B6BL.12.1 | B0024.9a.2 | Thioredoxin; Belongs to the thioredoxin family. | Probable thioredoxin-2; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. | 0.769 |
Y73B6BL.12 | trx-4 | Y73B6BL.12.1 | Y44E3A.3.1 | Thioredoxin; Belongs to the thioredoxin family. | Thioredoxin; Belongs to the thioredoxin family. | 0.621 |
cdk-1 | R05H5.3 | T05G5.3.2 | R05H5.3.1 | Cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II (By similarity). | Thioredoxin domain-containing protein. | 0.441 |
cdk-1 | ify-1 | T05G5.3.2 | C27A2.3.2 | Cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II (By similarity). | Securin-like protein; Acts as a chaperone and as an inhibitor for separase sep-1. Plays an essential role in maintaining chromosome cohesion prior to meiotic and mitotic anaphase, in cytokinesis and in organizing the spindle and the centrosome. Ubiquitination-dependent degradation at the onset of anaphase is likely to activate sep-1 resulting in the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes. Also required for cortical granule exocytosis. | 0.638 |
cdk-1 | nasp-2 | T05G5.3.2 | C50B6.2.1 | Cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II (By similarity). | SHNi-TPR domain-containing protein. | 0.643 |