STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
R06F6.8Guanine nucleotide exchange factor subunit R06F6.8; Probable component of a guanine nucleotide exchange factor (GEF) that may be required for efficient fusion of endosome-derived vesicles with the Golgi; Belongs to the RIC1 family. (1470 aa)    
Predicted Functional Partners:
M01F1.9
Uncharacterized protein.
   
 0.914
rab-33
Ras-related protein Rab-33.
   
 0.844
rab-6.1
Ras-related protein Rab-6.1; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family.
   
 0.844
rab-6.2
Ras-related protein Rab-6.2; Protein transport. Probably involved in vesicular traffic (By similarity).
    
 0.844
mon-2
Monensin-resistant homolog 2; May be required for traffic between late Golgi and early endosomes.
   
 
 0.770
cogc-8
Conserved oligomeric Golgi complex subunit 8; Required for normal Golgi function.
   
 
 0.593
rab-30
RAB family.
      
 0.592
C56E6.2
Uncharacterized protein.
    
 
 0.573
H35B03.1
Uncharacterized protein.
    
 
 0.573
Y54E10BR.2
Uncharacterized protein.
    
 
 0.573
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.