STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mpc-1Probable mitochondrial pyruvate carrier 1; May mediate the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (137 aa)    
Predicted Functional Partners:
mpc-2
Probable mitochondrial pyruvate carrier 2; May mediate the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
   
 
 0.949
snr-5
Probable small nuclear ribonucleoprotein F; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5.
   
    0.682
W09D6.1
AMP-binding domain-containing protein.
      
 0.502
men-1
Malic enzyme.
    
 
 0.498
Y94H6A.8
Probable NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
   
   0.479
cox-5B
Cytochrome OXidase assembly protein.
   
   0.470
ZK809.3
Uncharacterized protein.
   
 
 0.468
dad-1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit dad-1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across th [...]
   
    0.458
erg-28
Probable ergosterol biosynthetic protein 28 homolog; Promotes the translocation of slo-1 potassium ion channels from the endoplasmic reticulum to its final destination at the plasma membrane, probably by shielding from premature proteasomal degradation in the endoplasmic reticulum; Belongs to the ERG28 family.
   
    0.446
F59C6.5
Uncharacterized protein.
   
   0.436
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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