STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mag-1Protein mago nashi homolog; Involved in hermaphrodite germline sex determination. May allow oogenesis by inhibiting the function of one or more of the masculinizing genes (fog, fem, and gld) which act during the fourth larval stage to promote transient sperm production in the hermaphrodite germline; Belongs to the mago nashi family. (152 aa)    
Predicted Functional Partners:
rnp-4
RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.
   
 0.999
F33D11.10
Uncharacterized protein; Belongs to the DEAD box helicase family.
   
 
 0.995
T20G5.9
Mago-bind domain-containing protein.
   
 0.995
smg-4
Smg4_UPF3 domain-containing protein.
   
 0.988
W08E3.2
Btz domain-containing protein.
    
 0.984
hel-1
Spliceosome RNA helicase DDX39B homolog; Required for mRNA export out of the nucleus. May play a role in spliceosome assembly.
   
 0.929
cfim-1
Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]
   
 
 0.909
T16G12.6
Xpo1 domain-containing protein.
    
 
 0.904
rsp-6
Probable splicing factor, arginine/serine-rich 6; Plays a functionally redundant role in shifting germ cell sexual differentiation in hermaprodites. Required for the development of somatic gonad structures and for progression from larval stage to adulthood; Belongs to the splicing factor SR family.
   
 0.893
rnp-5
RRM domain-containing protein.
   
 0.871
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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