STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nac-2Sodium-dependent high-affinity dicarboxylate transporter 2; High-affinity sodium-dicarboxylate cotransporter that accepts a range of tricarboxylic acid-cycle intermediates with 4-5 carbon atoms. There is no interaction with monocarboxylates (By similarity). Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily. (585 aa)    
Predicted Functional Partners:
fgt-1
Facilitated glucose transporter protein 1; Facilitative glucose transporter that plays a role in glucose metabolism and regulation of longevity. May also play a role in lipid metabolism. Glucose transport activity of isoform a is competitively inhibited by mannose, galactose and fructose, suggesting ability to transport also other hexose sugars.
   
  
 0.725
atgp-1
Aamy domain-containing protein.
  
  
 0.668
glt-1
Excitatory amino acid transporter; Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium (By similarity).
    
 0.577
mlcd-1
MaLonyl CoA Decarboxylase.
    
 0.517
aat-6
Amino acid transporter protein 6; Amino acid transporter that mediates the uptake of the L- enantiomers of various amino acids, including L-glutamate (Probable). May play a role in promoting fertility.
  
  
 0.511
aat-9
Amino Acid Transporter.
  
  
 0.508
atgp-2
Aamy domain-containing protein.
  
  
 0.452
glt-5
Amino acid transporter.
  
 
 0.447
glt-3
Putative sodium-dependent excitatory amino acid transporter glt-3.
    
 0.440
glt-6
Putative sodium-dependent excitatory amino acid transporter glt-6.
    
 0.440
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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