STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
asp-4Aspartic protease 4; Aspartic protease, which is part of the necrosis cell death pathway. Involved in neuronal cell degeneration. Involved in heat stress response. Belongs to the peptidase A1 family. (444 aa)    
Predicted Functional Partners:
cpr-1
Gut-specific cysteine proteinase; Thiol protease. Has a role as a digestive enzyme. Belongs to the peptidase C1 family.
   
 0.958
cpr-6
Cathepsin B-like cysteine proteinase 6; Belongs to the peptidase C1 family.
   
 
 0.947
F57F5.1
Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.
   
 
 0.937
F32H5.1
Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.
   
 
 0.934
cpr-2
Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.
   
 
 0.932
cpr-4
Cathepsin B-like cysteine proteinase 4; Thiol protease which shows activity against the fluorogenic substrate z-Arg-Arg-AMC; Belongs to the peptidase C1 family.
   
 
 0.932
cpr-8
Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.
   
 
 0.932
W07B8.4
Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.
   
 
 0.932
cpr-5
Cathepsin B-like cysteine proteinase 5; Belongs to the peptidase C1 family.
   
 
 0.932
cpr-3
Cathepsin B-like cysteine proteinase 3; Belongs to the peptidase C1 family.
   
 
 0.927
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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