STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
R151.2Pribosyltran_N domain-containing protein. (446 aa)    
Predicted Functional Partners:
tkt-1
Transket_pyr domain-containing protein.
   
 
 0.979
F07A11.5
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
 0.979
rpia-1
Probable-ribose 5-phosphate isomerase; Belongs to the ribose 5-phosphate isomerase family.
  
 
 0.978
Y43F4B.5
Uncharacterized protein; Belongs to the phosphohexose mutase family.
  
 0.978
ppat-1
Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 0.970
W04G3.5
Pribosyltran_N domain-containing protein.
  
0.955
umps-1
Orotidine 5'-phosphate decarboxylase; Bifunctional enzyme which catalyzes the formation of UMP from orotate in the de novo pathway of pyrimidine biosynthesis. May also form UMP from uracil. Regulates the size of gut granules during embryonic development. Involved in resistance to DNA damaging agents including UV-C and X-ray radiation. In the C-terminal section; belongs to the OMP decarboxylase family.
  
 
 0.933
R05F9.6
Uncharacterized protein; Belongs to the phosphohexose mutase family.
   
 
 0.923
ndx-6
Putative nudix hydrolase 6; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family.
     
 0.906
F08F8.7
Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
  
  
 0.900
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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