node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aex-4 | ric-4 | T14G12.2.1 | Y22F5A.3b.1 | t-SNARE protein aex-4; t-SNARE protein which regulates the secretion of aex-5 from intestinal cells. Involved in the defecation motor program, which is a coordinated series of three muscle contractions that occurs every 45 seconds; Belongs to the SNAP-25 family. | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | 0.725 |
aex-4 | sec-22 | T14G12.2.1 | F55A4.1.1 | t-SNARE protein aex-4; t-SNARE protein which regulates the secretion of aex-5 from intestinal cells. Involved in the defecation motor program, which is a coordinated series of three muscle contractions that occurs every 45 seconds; Belongs to the SNAP-25 family. | Yeast SEC homolog; Belongs to the synaptobrevin family. | 0.816 |
aex-4 | snap-1 | T14G12.2.1 | D1014.3.2 | t-SNARE protein aex-4; t-SNARE protein which regulates the secretion of aex-5 from intestinal cells. Involved in the defecation motor program, which is a coordinated series of three muscle contractions that occurs every 45 seconds; Belongs to the SNAP-25 family. | SNAP (Soluble NSF Attachment Protein) homolog. | 0.900 |
aex-4 | snap-29 | T14G12.2.1 | K02D10.5.1 | t-SNARE protein aex-4; t-SNARE protein which regulates the secretion of aex-5 from intestinal cells. Involved in the defecation motor program, which is a coordinated series of three muscle contractions that occurs every 45 seconds; Belongs to the SNAP-25 family. | Soluble NSF attachment protein 29; SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion; Belongs to the SNAP-25 family. | 0.686 |
aex-4 | snb-1 | T14G12.2.1 | T10H9.4.1 | t-SNARE protein aex-4; t-SNARE protein which regulates the secretion of aex-5 from intestinal cells. Involved in the defecation motor program, which is a coordinated series of three muscle contractions that occurs every 45 seconds; Belongs to the SNAP-25 family. | Synaptobrevin-1; Involved in the targeting and/or fusion of transport vesicles to their target membrane. Acts in neuronal exocytosis of synaptic transmission. Likely to have a role in cholinergic transmisson. Required for viability, coordinated movement and M3 pharynx motor neuron function. | 0.762 |
aex-4 | syx-17 | T14G12.2.1 | VF39H2L.1.1 | t-SNARE protein aex-4; t-SNARE protein which regulates the secretion of aex-5 from intestinal cells. Involved in the defecation motor program, which is a coordinated series of three muscle contractions that occurs every 45 seconds; Belongs to the SNAP-25 family. | t-SNARE coiled-coil homology domain-containing protein. | 0.832 |
aex-4 | syx-2 | T14G12.2.1 | F48F7.2.2 | t-SNARE protein aex-4; t-SNARE protein which regulates the secretion of aex-5 from intestinal cells. Involved in the defecation motor program, which is a coordinated series of three muscle contractions that occurs every 45 seconds; Belongs to the SNAP-25 family. | Putative syntaxin-2; Potentially involved in docking of synaptic vesicles at presynaptic active zones; Belongs to the syntaxin family. | 0.730 |
aex-4 | syx-4 | T14G12.2.1 | T01B11.3.1 | t-SNARE protein aex-4; t-SNARE protein which regulates the secretion of aex-5 from intestinal cells. Involved in the defecation motor program, which is a coordinated series of three muscle contractions that occurs every 45 seconds; Belongs to the SNAP-25 family. | Putative syntaxin-4; Potentially involved in docking of synaptic vesicles at presynaptic active zones. | 0.815 |
aex-4 | syx-6 | T14G12.2.1 | C15C7.1.1 | t-SNARE protein aex-4; t-SNARE protein which regulates the secretion of aex-5 from intestinal cells. Involved in the defecation motor program, which is a coordinated series of three muscle contractions that occurs every 45 seconds; Belongs to the SNAP-25 family. | Putative syntaxin 6; Potentially involved in docking of synaptic vesicles at presynaptic active zones; Belongs to the syntaxin family. | 0.843 |
aex-4 | unc-64 | T14G12.2.1 | F56A8.7a.2 | t-SNARE protein aex-4; t-SNARE protein which regulates the secretion of aex-5 from intestinal cells. Involved in the defecation motor program, which is a coordinated series of three muscle contractions that occurs every 45 seconds; Belongs to the SNAP-25 family. | Syntaxin-1A homolog; Plays a critical role in several secretory processes, including cuticle secretion and neurotransmitter release, and probably assists in neuronal membrane maturation or the final stages of neuronal differentiation. Essential for embryonic viability and development. Has a role in dauer formation and adult life span. Required for locomotion. Probably by regulating neuronal transmission downstream of lin-3 and receptor lin-23 and phospholipase plc-3 and upstream of innexin unc-7 and egl-4/PKG in ALA neurons, involved in the decrease in pharyngeal pumping during the qui [...] | 0.778 |
ric-4 | aex-4 | Y22F5A.3b.1 | T14G12.2.1 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | t-SNARE protein aex-4; t-SNARE protein which regulates the secretion of aex-5 from intestinal cells. Involved in the defecation motor program, which is a coordinated series of three muscle contractions that occurs every 45 seconds; Belongs to the SNAP-25 family. | 0.725 |
ric-4 | sec-22 | Y22F5A.3b.1 | F55A4.1.1 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | Yeast SEC homolog; Belongs to the synaptobrevin family. | 0.816 |
ric-4 | snap-1 | Y22F5A.3b.1 | D1014.3.2 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | SNAP (Soluble NSF Attachment Protein) homolog. | 0.950 |
ric-4 | snap-29 | Y22F5A.3b.1 | K02D10.5.1 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | Soluble NSF attachment protein 29; SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion; Belongs to the SNAP-25 family. | 0.697 |
ric-4 | snb-1 | Y22F5A.3b.1 | T10H9.4.1 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | Synaptobrevin-1; Involved in the targeting and/or fusion of transport vesicles to their target membrane. Acts in neuronal exocytosis of synaptic transmission. Likely to have a role in cholinergic transmisson. Required for viability, coordinated movement and M3 pharynx motor neuron function. | 0.991 |
ric-4 | syx-17 | Y22F5A.3b.1 | VF39H2L.1.1 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | t-SNARE coiled-coil homology domain-containing protein. | 0.795 |
ric-4 | syx-2 | Y22F5A.3b.1 | F48F7.2.2 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | Putative syntaxin-2; Potentially involved in docking of synaptic vesicles at presynaptic active zones; Belongs to the syntaxin family. | 0.821 |
ric-4 | syx-4 | Y22F5A.3b.1 | T01B11.3.1 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | Putative syntaxin-4; Potentially involved in docking of synaptic vesicles at presynaptic active zones. | 0.787 |
ric-4 | syx-6 | Y22F5A.3b.1 | C15C7.1.1 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | Putative syntaxin 6; Potentially involved in docking of synaptic vesicles at presynaptic active zones; Belongs to the syntaxin family. | 0.841 |
ric-4 | unc-64 | Y22F5A.3b.1 | F56A8.7a.2 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | Syntaxin-1A homolog; Plays a critical role in several secretory processes, including cuticle secretion and neurotransmitter release, and probably assists in neuronal membrane maturation or the final stages of neuronal differentiation. Essential for embryonic viability and development. Has a role in dauer formation and adult life span. Required for locomotion. Probably by regulating neuronal transmission downstream of lin-3 and receptor lin-23 and phospholipase plc-3 and upstream of innexin unc-7 and egl-4/PKG in ALA neurons, involved in the decrease in pharyngeal pumping during the qui [...] | 0.993 |