STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
twk-21TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (581 aa)    
Predicted Functional Partners:
ascc-1
KH domain-containing protein.
   
  
 0.475
cft-1
Cystic Fibrosis Transmembrane conductance regulator homolog.
   
 
 0.470
srh-179
Serpentine Receptor, class H.
   
  
 0.469
ari-1.2
RBR-type E3 ubiquitin transferase.
   
  
 0.468
C56E10.3
Uncharacterized protein.
   
  
 0.468
str-151
Seven TM Receptor.
   
  
 0.468
C27F2.6
Uncharacterized protein.
      
 0.467
srh-184
Serpentine Receptor, class H.
      
 0.467
str-116
Seven TM Receptor.
      
 0.467
F16B4.6
Uncharacterized protein.
      
 0.467
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.