node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aha-1 | cky-1 | C25A1.11a.1 | C15C8.2.1 | Aryl hydrocarbon receptor nuclear translocator homolog; Has a role in cellular differentiation. Required for pharyngeal development. In collaboration with ahr-1 it is involved in RMEL/R and SDQR neuron cell migration. Acts in the cellular response to hypoxia. Involved in aggregation behavior by regulating soluble guanylate cyclase gene expression in the URX neurons. | BHLH-PAS factor. | 0.999 |
aha-1 | hlh-34 | C25A1.11a.1 | T01D3.2.1 | Aryl hydrocarbon receptor nuclear translocator homolog; Has a role in cellular differentiation. Required for pharyngeal development. In collaboration with ahr-1 it is involved in RMEL/R and SDQR neuron cell migration. Acts in the cellular response to hypoxia. Involved in aggregation behavior by regulating soluble guanylate cyclase gene expression in the URX neurons. | Helix-loop-helix 34; Transcription factor that may be a master gene of CNS development in cooperation with Arnt. It may have pleiotropic effects in the tissues expressed during development (By similarity). | 0.966 |
ceh-10 | fax-1 | W03A3.1.1 | F56E3.4a.1 | Homeobox protein ceh-10; Required for larval development and for cell fate specification and migration of CAN neurons. | Nuclear receptor domain-containing protein. | 0.559 |
ceh-10 | hlh-34 | W03A3.1.1 | T01D3.2.1 | Homeobox protein ceh-10; Required for larval development and for cell fate specification and migration of CAN neurons. | Helix-loop-helix 34; Transcription factor that may be a master gene of CNS development in cooperation with Arnt. It may have pleiotropic effects in the tissues expressed during development (By similarity). | 0.551 |
cky-1 | aha-1 | C15C8.2.1 | C25A1.11a.1 | BHLH-PAS factor. | Aryl hydrocarbon receptor nuclear translocator homolog; Has a role in cellular differentiation. Required for pharyngeal development. In collaboration with ahr-1 it is involved in RMEL/R and SDQR neuron cell migration. Acts in the cellular response to hypoxia. Involved in aggregation behavior by regulating soluble guanylate cyclase gene expression in the URX neurons. | 0.999 |
cky-1 | hlh-34 | C15C8.2.1 | T01D3.2.1 | BHLH-PAS factor. | Helix-loop-helix 34; Transcription factor that may be a master gene of CNS development in cooperation with Arnt. It may have pleiotropic effects in the tissues expressed during development (By similarity). | 0.816 |
cky-1 | unc-42 | C15C8.2.1 | F58E6.10b.1 | BHLH-PAS factor. | Homeobox domain-containing protein. | 0.491 |
fax-1 | ceh-10 | F56E3.4a.1 | W03A3.1.1 | Nuclear receptor domain-containing protein. | Homeobox protein ceh-10; Required for larval development and for cell fate specification and migration of CAN neurons. | 0.559 |
fax-1 | hlh-34 | F56E3.4a.1 | T01D3.2.1 | Nuclear receptor domain-containing protein. | Helix-loop-helix 34; Transcription factor that may be a master gene of CNS development in cooperation with Arnt. It may have pleiotropic effects in the tissues expressed during development (By similarity). | 0.581 |
fax-1 | unc-42 | F56E3.4a.1 | F58E6.10b.1 | Nuclear receptor domain-containing protein. | Homeobox domain-containing protein. | 0.763 |
gcy-21 | hlh-34 | F22E5.3.1 | T01D3.2.1 | Receptor-type guanylate cyclase gcy-21; Guanylate cyclase involved in the production of the second messenger cGMP (By similarity). | Helix-loop-helix 34; Transcription factor that may be a master gene of CNS development in cooperation with Arnt. It may have pleiotropic effects in the tissues expressed during development (By similarity). | 0.660 |
gcy-21 | inx-17 | F22E5.3.1 | R12E2.4a.1 | Receptor-type guanylate cyclase gcy-21; Guanylate cyclase involved in the production of the second messenger cGMP (By similarity). | Innexin-17; Structural component of the gap junctions. | 0.660 |
gcy-21 | xdh-1 | F22E5.3.1 | F55B11.1.1 | Receptor-type guanylate cyclase gcy-21; Guanylate cyclase involved in the production of the second messenger cGMP (By similarity). | Xanthine DeHydrogenase homolog. | 0.695 |
hlh-26 | hlh-34 | C17C3.8.1 | T01D3.2.1 | Helix-loop-helix protein 26; Binds DNA via the E-box sequence 5'-CACGTG-3'. Binds DNA as a homodimer. Represses lag-2 transcription during embryogenesis via Notch signaling, in an unc-37-dependent manner. Also represses tbx-37 independent of Notch signaling. | Helix-loop-helix 34; Transcription factor that may be a master gene of CNS development in cooperation with Arnt. It may have pleiotropic effects in the tissues expressed during development (By similarity). | 0.530 |
hlh-34 | aha-1 | T01D3.2.1 | C25A1.11a.1 | Helix-loop-helix 34; Transcription factor that may be a master gene of CNS development in cooperation with Arnt. It may have pleiotropic effects in the tissues expressed during development (By similarity). | Aryl hydrocarbon receptor nuclear translocator homolog; Has a role in cellular differentiation. Required for pharyngeal development. In collaboration with ahr-1 it is involved in RMEL/R and SDQR neuron cell migration. Acts in the cellular response to hypoxia. Involved in aggregation behavior by regulating soluble guanylate cyclase gene expression in the URX neurons. | 0.966 |
hlh-34 | ceh-10 | T01D3.2.1 | W03A3.1.1 | Helix-loop-helix 34; Transcription factor that may be a master gene of CNS development in cooperation with Arnt. It may have pleiotropic effects in the tissues expressed during development (By similarity). | Homeobox protein ceh-10; Required for larval development and for cell fate specification and migration of CAN neurons. | 0.551 |
hlh-34 | cky-1 | T01D3.2.1 | C15C8.2.1 | Helix-loop-helix 34; Transcription factor that may be a master gene of CNS development in cooperation with Arnt. It may have pleiotropic effects in the tissues expressed during development (By similarity). | BHLH-PAS factor. | 0.816 |
hlh-34 | fax-1 | T01D3.2.1 | F56E3.4a.1 | Helix-loop-helix 34; Transcription factor that may be a master gene of CNS development in cooperation with Arnt. It may have pleiotropic effects in the tissues expressed during development (By similarity). | Nuclear receptor domain-containing protein. | 0.581 |
hlh-34 | gcy-21 | T01D3.2.1 | F22E5.3.1 | Helix-loop-helix 34; Transcription factor that may be a master gene of CNS development in cooperation with Arnt. It may have pleiotropic effects in the tissues expressed during development (By similarity). | Receptor-type guanylate cyclase gcy-21; Guanylate cyclase involved in the production of the second messenger cGMP (By similarity). | 0.660 |
hlh-34 | hlh-26 | T01D3.2.1 | C17C3.8.1 | Helix-loop-helix 34; Transcription factor that may be a master gene of CNS development in cooperation with Arnt. It may have pleiotropic effects in the tissues expressed during development (By similarity). | Helix-loop-helix protein 26; Binds DNA via the E-box sequence 5'-CACGTG-3'. Binds DNA as a homodimer. Represses lag-2 transcription during embryogenesis via Notch signaling, in an unc-37-dependent manner. Also represses tbx-37 independent of Notch signaling. | 0.530 |