Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| F20D1.3 | T04A8.8 | F20D1.3.1 | T04A8.8.1 | Uncharacterized protein. | Rad60-SLD domain-containing protein. | 0.803 |
| F20D1.3 | aos-1 | F20D1.3.1 | C08B6.9.1 | Uncharacterized protein. | SUMO-activating enzyme subunit aos-1; The dimeric enzyme acts as an E1 ligase for smo-1. It mediates ATP-dependent activation of smo-1 and formation of a thioester with a conserved cysteine residue on uba-2 (Probable). | 0.515 |
| F20D1.3 | gei-17 | F20D1.3.1 | W10D5.3c.3 | Uncharacterized protein. | E3 SUMO-protein ligase gei-17; Functions as an E3-type smo-1 ligase. Mediates smo-1 conjugation to air-2 in vitro and is required for proper chromosome alignment. In the early embryo, specifically suppresses checkpoint activation in response to DNA damage, maybe by promoting mus-101 sumoylation. In embryos, plays a role in determining telomere localization in the nucleus. | 0.406 |
| F20D1.3 | ran-2 | F20D1.3.1 | C29E4.3a.1 | Uncharacterized protein. | Ran GTPase-activating protein 2; GTPase system comprising ran-1, ran-2 and ran-3 is essential in nucleocytoplasmic trafficking. Ran-2 is a GTPase activator for the nuclear RAS-related regulatory protein Ran, converting it to the putatively inactive GDP-bound state. Required for correct chromosome alignment and segregation on the metaphase plate. | 0.684 |
| F20D1.3 | uba-2 | F20D1.3.1 | W02A11.4.1 | Uncharacterized protein. | SUMO-activating enzyme subunit uba-2; The dimeric enzyme acts as an E1 ligase for smo-1. It mediates ATP-dependent activation of smo-1 and formation of a thioester with a conserved cysteine residue on uba-2 (Probable). | 0.530 |
| T04A8.8 | F20D1.3 | T04A8.8.1 | F20D1.3.1 | Rad60-SLD domain-containing protein. | Uncharacterized protein. | 0.803 |
| T04A8.8 | aos-1 | T04A8.8.1 | C08B6.9.1 | Rad60-SLD domain-containing protein. | SUMO-activating enzyme subunit aos-1; The dimeric enzyme acts as an E1 ligase for smo-1. It mediates ATP-dependent activation of smo-1 and formation of a thioester with a conserved cysteine residue on uba-2 (Probable). | 0.956 |
| T04A8.8 | eef-1G | T04A8.8.1 | F17C11.9a.1 | Rad60-SLD domain-containing protein. | Probable elongation factor 1-gamma; Probably plays a role in anchoring the complex to other cellular components. | 0.836 |
| T04A8.8 | gei-17 | T04A8.8.1 | W10D5.3c.3 | Rad60-SLD domain-containing protein. | E3 SUMO-protein ligase gei-17; Functions as an E3-type smo-1 ligase. Mediates smo-1 conjugation to air-2 in vitro and is required for proper chromosome alignment. In the early embryo, specifically suppresses checkpoint activation in response to DNA damage, maybe by promoting mus-101 sumoylation. In embryos, plays a role in determining telomere localization in the nucleus. | 0.787 |
| T04A8.8 | miz-1 | T04A8.8.1 | R13.4a.1 | Rad60-SLD domain-containing protein. | SP-RING-type domain-containing protein. | 0.787 |
| T04A8.8 | ned-8 | T04A8.8.1 | F45H11.2.1 | Rad60-SLD domain-containing protein. | NEDD8; Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex uba-3-ula-1 and linkage to the E2 enzyme ubc-12. Attachment of ned-8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins. | 0.829 |
| T04A8.8 | pcn-1 | T04A8.8.1 | W03D2.4.1 | Rad60-SLD domain-containing protein. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.919 |
| T04A8.8 | ran-2 | T04A8.8.1 | C29E4.3a.1 | Rad60-SLD domain-containing protein. | Ran GTPase-activating protein 2; GTPase system comprising ran-1, ran-2 and ran-3 is essential in nucleocytoplasmic trafficking. Ran-2 is a GTPase activator for the nuclear RAS-related regulatory protein Ran, converting it to the putatively inactive GDP-bound state. Required for correct chromosome alignment and segregation on the metaphase plate. | 0.821 |
| T04A8.8 | uba-2 | T04A8.8.1 | W02A11.4.1 | Rad60-SLD domain-containing protein. | SUMO-activating enzyme subunit uba-2; The dimeric enzyme acts as an E1 ligase for smo-1. It mediates ATP-dependent activation of smo-1 and formation of a thioester with a conserved cysteine residue on uba-2 (Probable). | 0.921 |
| T04A8.8 | ulp-1 | T04A8.8.1 | T10F2.3.1 | Rad60-SLD domain-containing protein. | Sentrin-specific protease; Protease that deconjugates smo-1 from targeted proteins and may catalyze the processing of smo-1 to its mature form. | 0.815 |
| aos-1 | F20D1.3 | C08B6.9.1 | F20D1.3.1 | SUMO-activating enzyme subunit aos-1; The dimeric enzyme acts as an E1 ligase for smo-1. It mediates ATP-dependent activation of smo-1 and formation of a thioester with a conserved cysteine residue on uba-2 (Probable). | Uncharacterized protein. | 0.515 |
| aos-1 | T04A8.8 | C08B6.9.1 | T04A8.8.1 | SUMO-activating enzyme subunit aos-1; The dimeric enzyme acts as an E1 ligase for smo-1. It mediates ATP-dependent activation of smo-1 and formation of a thioester with a conserved cysteine residue on uba-2 (Probable). | Rad60-SLD domain-containing protein. | 0.956 |
| aos-1 | gei-17 | C08B6.9.1 | W10D5.3c.3 | SUMO-activating enzyme subunit aos-1; The dimeric enzyme acts as an E1 ligase for smo-1. It mediates ATP-dependent activation of smo-1 and formation of a thioester with a conserved cysteine residue on uba-2 (Probable). | E3 SUMO-protein ligase gei-17; Functions as an E3-type smo-1 ligase. Mediates smo-1 conjugation to air-2 in vitro and is required for proper chromosome alignment. In the early embryo, specifically suppresses checkpoint activation in response to DNA damage, maybe by promoting mus-101 sumoylation. In embryos, plays a role in determining telomere localization in the nucleus. | 0.898 |
| aos-1 | miz-1 | C08B6.9.1 | R13.4a.1 | SUMO-activating enzyme subunit aos-1; The dimeric enzyme acts as an E1 ligase for smo-1. It mediates ATP-dependent activation of smo-1 and formation of a thioester with a conserved cysteine residue on uba-2 (Probable). | SP-RING-type domain-containing protein. | 0.528 |
| aos-1 | ned-8 | C08B6.9.1 | F45H11.2.1 | SUMO-activating enzyme subunit aos-1; The dimeric enzyme acts as an E1 ligase for smo-1. It mediates ATP-dependent activation of smo-1 and formation of a thioester with a conserved cysteine residue on uba-2 (Probable). | NEDD8; Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex uba-3-ula-1 and linkage to the E2 enzyme ubc-12. Attachment of ned-8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins. | 0.646 |
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