node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C28A5.1 | T04F3.1 | C28A5.1.1 | T04F3.1a.1 | Uncharacterized protein. | Aminotran_1_2 domain-containing protein. | 0.614 |
C28A5.1 | alh-13 | C28A5.1.1 | T22H6.2b.1 | Uncharacterized protein. | Probable delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.694 |
C28A5.1 | pyr-1 | C28A5.1.1 | D2085.1.1 | Uncharacterized protein. | Glutamine-dependent carbamoyl-phosphate synthase; This protein is a 'fusion' protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) (By similarity). Involved in the elongation of the pharyngeal isthmus during development, probably by providing precursors of UDP- sugars required for heparan sulfate proteoglycan biosynthesis. Regulates the organization of the actin and intermediate filaments cytoskeleton in the pharyngeal muscles ; In the central section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily. | 0.787 |
C28A5.2 | T04F3.1 | C28A5.2.1 | T04F3.1a.1 | Uncharacterized protein. | Aminotran_1_2 domain-containing protein. | 0.614 |
C28A5.2 | alh-13 | C28A5.2.1 | T22H6.2b.1 | Uncharacterized protein. | Probable delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.694 |
C28A5.2 | pyr-1 | C28A5.2.1 | D2085.1.1 | Uncharacterized protein. | Glutamine-dependent carbamoyl-phosphate synthase; This protein is a 'fusion' protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) (By similarity). Involved in the elongation of the pharyngeal isthmus during development, probably by providing precursors of UDP- sugars required for heparan sulfate proteoglycan biosynthesis. Regulates the organization of the actin and intermediate filaments cytoskeleton in the pharyngeal muscles ; In the central section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily. | 0.787 |
F53F10.2 | T04F3.1 | F53F10.2a.1 | T04F3.1a.1 | Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | Aminotran_1_2 domain-containing protein. | 0.615 |
F53F10.2 | alh-13 | F53F10.2a.1 | T22H6.2b.1 | Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | Probable delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.699 |
F53F10.2 | odc-1 | F53F10.2a.1 | K11C4.4.1 | Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | Ornithine decarboxylase; Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis. | 0.578 |
F53F10.2 | pyr-1 | F53F10.2a.1 | D2085.1.1 | Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | Glutamine-dependent carbamoyl-phosphate synthase; This protein is a 'fusion' protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) (By similarity). Involved in the elongation of the pharyngeal isthmus during development, probably by providing precursors of UDP- sugars required for heparan sulfate proteoglycan biosynthesis. Regulates the organization of the actin and intermediate filaments cytoskeleton in the pharyngeal muscles ; In the central section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily. | 0.790 |
T04F3.1 | C28A5.1 | T04F3.1a.1 | C28A5.1.1 | Aminotran_1_2 domain-containing protein. | Uncharacterized protein. | 0.614 |
T04F3.1 | C28A5.2 | T04F3.1a.1 | C28A5.2.1 | Aminotran_1_2 domain-containing protein. | Uncharacterized protein. | 0.614 |
T04F3.1 | F53F10.2 | T04F3.1a.1 | F53F10.2a.1 | Aminotran_1_2 domain-containing protein. | Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.615 |
T04F3.1 | alh-13 | T04F3.1a.1 | T22H6.2b.1 | Aminotran_1_2 domain-containing protein. | Probable delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.794 |
T04F3.1 | flcn-1 | T04F3.1a.1 | F22D3.2a.1 | Aminotran_1_2 domain-containing protein. | UDENN FLCN/SMCR8-type domain-containing protein. | 0.713 |
T04F3.1 | kynu-1 | T04F3.1a.1 | C15H9.7.1 | Aminotran_1_2 domain-containing protein. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. | 0.630 |
T04F3.1 | men-1 | T04F3.1a.1 | Y48B6A.12.2 | Aminotran_1_2 domain-containing protein. | Malic enzyme. | 0.615 |
T04F3.1 | odc-1 | T04F3.1a.1 | K11C4.4.1 | Aminotran_1_2 domain-containing protein. | Ornithine decarboxylase; Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis. | 0.614 |
T04F3.1 | pyr-1 | T04F3.1a.1 | D2085.1.1 | Aminotran_1_2 domain-containing protein. | Glutamine-dependent carbamoyl-phosphate synthase; This protein is a 'fusion' protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) (By similarity). Involved in the elongation of the pharyngeal isthmus during development, probably by providing precursors of UDP- sugars required for heparan sulfate proteoglycan biosynthesis. Regulates the organization of the actin and intermediate filaments cytoskeleton in the pharyngeal muscles ; In the central section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily. | 0.631 |
T04F3.1 | tdo-2 | T04F3.1a.1 | C28H8.11a.2 | Aminotran_1_2 domain-containing protein. | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. Involved in regulation of protein homeostasis, longevity and reproducive life span. Specifically regulates proteotoxicity due to age-related aggregation of proteins like alpha- synuclein, via its effects on tryptophan metabolism. | 0.614 |