STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
T06G6.3Uncharacterized protein. (511 aa)    
Predicted Functional Partners:
F37A4.6
Uncharacterized protein F37A4.6.
   
  
 0.857
B0379.1
Uncharacterized protein.
      
 0.851
R10E8.8
F-box domain-containing protein.
      
 0.851
Y53G8AL.1
FHA domain-containing protein.
      
 0.851
T01G5.1
Protein kinase domain-containing protein.
      
 0.807
nex-4
AnNEXin family.
   
  
 0.701
C03H5.6
BTB domain-containing protein.
   
  
 0.636
C11E4.6
Uncharacterized protein.
   
  
 0.545
H06I04.1
Uncharacterized protein.
      
 0.533
gpa-3
Guanine nucleotide-binding protein alpha-3 subunit; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Promotes transcription of 3',5'-cyclic phosphodiesterases pde- 1 and pde-5, leading to reduced cGMP levels in sensory neurons. This causes suppression of insulin production and signaling which leads to increased daf-16 activity and contributes to increased adult lifespan and resistance to oxidative stress. In addition, by reducing cGMP levels, inhibits TGF-beta signaling pathways. Involved in behaviora [...]
   
    0.529
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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