STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
unc-58Uncoordinated protein 58; Has a role in mobility, possibly in the transport of potassium in muscles; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (591 aa)    
Predicted Functional Partners:
twk-14
TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
   
 
 0.905
M70.5
Uncharacterized protein.
      
 0.808
dpy-10
Cuticle collagen dpy-10; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment.
      
 0.697
sws-1
SWIM-type domain-containing protein.
      
 0.667
sup-9
Two pore potassium channel protein sup-9; Potassium channel involved in coordination of muscle contraction. Activity is regulated by sup-18 ; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
   
 
0.656
snrp-27
SNRNP27 domain-containing protein.
      
 0.626
egl-23
Uncharacterized protein; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
   
 
0.613
twk-7
TWiK family of potassium channels protein 7.
   
 
0.578
twk-2
TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
   
 
0.574
twk-20
Two pore potassium channel protein sup-9.
   
 
0.551
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.