Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| chk-2 | hal-2 | Y60A3A.12.1 | T16H12.11.1 | Serine/threonine-protein kinase chk-2; Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest, activation of DNA repair and apoptosis in response to the presence of DNA double-strand breaks. May also negatively regulate cell cycle progression during unperturbed cell cycles. Phosphorylates and inhibits cdc25 phosphatase, preventing entry into mitosis. Required for nuclear reorganization and homologous chromosome pairing during meiotic prophase. | Uncharacterized protein. | 0.698 |
| chk-2 | him-3 | Y60A3A.12.1 | ZK381.1a.2 | Serine/threonine-protein kinase chk-2; Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest, activation of DNA repair and apoptosis in response to the presence of DNA double-strand breaks. May also negatively regulate cell cycle progression during unperturbed cell cycles. Phosphorylates and inhibits cdc25 phosphatase, preventing entry into mitosis. Required for nuclear reorganization and homologous chromosome pairing during meiotic prophase. | HORMA domain-containing protein. | 0.713 |
| chk-2 | htp-1 | Y60A3A.12.1 | F41H10.10.1 | Serine/threonine-protein kinase chk-2; Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest, activation of DNA repair and apoptosis in response to the presence of DNA double-strand breaks. May also negatively regulate cell cycle progression during unperturbed cell cycles. Phosphorylates and inhibits cdc25 phosphatase, preventing entry into mitosis. Required for nuclear reorganization and homologous chromosome pairing during meiotic prophase. | HORMA domain-containing protein. | 0.759 |
| chk-2 | htp-3 | Y60A3A.12.1 | F57C9.5.1 | Serine/threonine-protein kinase chk-2; Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest, activation of DNA repair and apoptosis in response to the presence of DNA double-strand breaks. May also negatively regulate cell cycle progression during unperturbed cell cycles. Phosphorylates and inhibits cdc25 phosphatase, preventing entry into mitosis. Required for nuclear reorganization and homologous chromosome pairing during meiotic prophase. | HORMA domain-containing protein. | 0.717 |
| chk-2 | rad-51 | Y60A3A.12.1 | Y43C5A.6a.1 | Serine/threonine-protein kinase chk-2; Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest, activation of DNA repair and apoptosis in response to the presence of DNA double-strand breaks. May also negatively regulate cell cycle progression during unperturbed cell cycles. Phosphorylates and inhibits cdc25 phosphatase, preventing entry into mitosis. Required for nuclear reorganization and homologous chromosome pairing during meiotic prophase. | DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. | 0.909 |
| chk-2 | spo-11 | Y60A3A.12.1 | T05E11.4a.1 | Serine/threonine-protein kinase chk-2; Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest, activation of DNA repair and apoptosis in response to the presence of DNA double-strand breaks. May also negatively regulate cell cycle progression during unperturbed cell cycles. Phosphorylates and inhibits cdc25 phosphatase, preventing entry into mitosis. Required for nuclear reorganization and homologous chromosome pairing during meiotic prophase. | Meiotic recombination protein spo-11; Required for meiotic recombination. Mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. | 0.893 |
| chk-2 | sun-1 | Y60A3A.12.1 | F57B1.2.1 | Serine/threonine-protein kinase chk-2; Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest, activation of DNA repair and apoptosis in response to the presence of DNA double-strand breaks. May also negatively regulate cell cycle progression during unperturbed cell cycles. Phosphorylates and inhibits cdc25 phosphatase, preventing entry into mitosis. Required for nuclear reorganization and homologous chromosome pairing during meiotic prophase. | Sun domain-containing protein 1; Involved in centrosome attachment to the nucleus. Required for zyg-12 localization to the nuclear envelope. Together with pot-1, it is required to anchor telomeres to the nuclear envelope in embryos. | 0.898 |
| chk-2 | syp-2 | Y60A3A.12.1 | C24G6.1.1 | Serine/threonine-protein kinase chk-2; Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest, activation of DNA repair and apoptosis in response to the presence of DNA double-strand breaks. May also negatively regulate cell cycle progression during unperturbed cell cycles. Phosphorylates and inhibits cdc25 phosphatase, preventing entry into mitosis. Required for nuclear reorganization and homologous chromosome pairing during meiotic prophase. | Uncharacterized protein. | 0.704 |
| chk-2 | zim-1 | Y60A3A.12.1 | T07G12.6b.1 | Serine/threonine-protein kinase chk-2; Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest, activation of DNA repair and apoptosis in response to the presence of DNA double-strand breaks. May also negatively regulate cell cycle progression during unperturbed cell cycles. Phosphorylates and inhibits cdc25 phosphatase, preventing entry into mitosis. Required for nuclear reorganization and homologous chromosome pairing during meiotic prophase. | C2H2-type domain-containing protein. | 0.766 |
| chk-2 | zyg-12 | Y60A3A.12.1 | ZK546.1b.1 | Serine/threonine-protein kinase chk-2; Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest, activation of DNA repair and apoptosis in response to the presence of DNA double-strand breaks. May also negatively regulate cell cycle progression during unperturbed cell cycles. Phosphorylates and inhibits cdc25 phosphatase, preventing entry into mitosis. Required for nuclear reorganization and homologous chromosome pairing during meiotic prophase. | Zygote defective protein 12; Cytoskeletal linker protein, which is essential for attachment of the centrosome to the nucleus. Required for dynein localization to the nuclear envelope. Forms a LINC (LInker of Nucleoskeleton and Cytoskeleton) complex together with unc-84, that may be involved in DNA damage repair ; Belongs to the hook family. | 0.842 |
| hal-2 | chk-2 | T16H12.11.1 | Y60A3A.12.1 | Uncharacterized protein. | Serine/threonine-protein kinase chk-2; Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest, activation of DNA repair and apoptosis in response to the presence of DNA double-strand breaks. May also negatively regulate cell cycle progression during unperturbed cell cycles. Phosphorylates and inhibits cdc25 phosphatase, preventing entry into mitosis. Required for nuclear reorganization and homologous chromosome pairing during meiotic prophase. | 0.698 |
| hal-2 | him-3 | T16H12.11.1 | ZK381.1a.2 | Uncharacterized protein. | HORMA domain-containing protein. | 0.720 |
| hal-2 | htp-1 | T16H12.11.1 | F41H10.10.1 | Uncharacterized protein. | HORMA domain-containing protein. | 0.720 |
| hal-2 | htp-3 | T16H12.11.1 | F57C9.5.1 | Uncharacterized protein. | HORMA domain-containing protein. | 0.722 |
| hal-2 | spo-11 | T16H12.11.1 | T05E11.4a.1 | Uncharacterized protein. | Meiotic recombination protein spo-11; Required for meiotic recombination. Mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. | 0.470 |
| hal-2 | sun-1 | T16H12.11.1 | F57B1.2.1 | Uncharacterized protein. | Sun domain-containing protein 1; Involved in centrosome attachment to the nucleus. Required for zyg-12 localization to the nuclear envelope. Together with pot-1, it is required to anchor telomeres to the nuclear envelope in embryos. | 0.713 |
| hal-2 | syp-2 | T16H12.11.1 | C24G6.1.1 | Uncharacterized protein. | Uncharacterized protein. | 0.510 |
| hal-2 | zim-1 | T16H12.11.1 | T07G12.6b.1 | Uncharacterized protein. | C2H2-type domain-containing protein. | 0.720 |
| him-3 | chk-2 | ZK381.1a.2 | Y60A3A.12.1 | HORMA domain-containing protein. | Serine/threonine-protein kinase chk-2; Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest, activation of DNA repair and apoptosis in response to the presence of DNA double-strand breaks. May also negatively regulate cell cycle progression during unperturbed cell cycles. Phosphorylates and inhibits cdc25 phosphatase, preventing entry into mitosis. Required for nuclear reorganization and homologous chromosome pairing during meiotic prophase. | 0.713 |
| him-3 | hal-2 | ZK381.1a.2 | T16H12.11.1 | HORMA domain-containing protein. | Uncharacterized protein. | 0.720 |
page 1 of 6