STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
alh-5Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (437 aa)    
Predicted Functional Partners:
acs-19
Acetyl-coenzyme A synthetase.
  
 0.981
gta-1
Probable 4-aminobutyrate aminotransferase, mitochondrial.
  
 0.965
T09B4.8
Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.957
unc-25
Glutamic acid decarboxylase.
   
 0.951
alh-8
Probable methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA (By similarity); Belongs to the aldehyde dehydrogenase family.
   
0.932
B0250.5
Probable 3-hydroxyisobutyrate dehydrogenase, mitochondrial.
   
 
 0.931
C13B9.2
Uncharacterized protein C13B9.2; Belongs to the glycerate kinase type-2 family.
   
 
 0.930
gbh-1
Probable gamma-butyrobetaine dioxygenase; Catalyzes the formation of L-carnitine from gamma- butyrobetaine.
   
 0.929
H24K24.3
Alcohol dehydrogenase class-3; Class-III ADH is remarkably ineffective in oxidizing ethanol, but it readily catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione (By similarity). Plays a role in the calcium flux to the cytoplasm in the ASJ sensory neurons upon removal of a nitric oxide stimulus.
 
 0.927
upb-1
CN hydrolase domain-containing protein.
   
 0.925
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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