node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
agmo-1 | pah-1 | BE10.2.1 | K08F8.4a.1 | Alkylglycerol monooxygenase; Glyceryl-ether monooxygenase that cleaves the O-alkyl bond of ether lipids; Belongs to the sterol desaturase family. TMEM195 subfamily. | Phenylalanine-4-hydroxylase; Catalyzes the hydroxylation of L-phenylalanine to L-tyrosine. Catalyzes the hydroxylation of tryptophan to 5-hydroxy-L-tryptophan. Plays a role in the biosynthesis of a melanin-like cuticle pigment. Belongs to the biopterin-dependent aromatic amino acid hydroxylase family. | 0.687 |
agmo-1 | pcbd-1 | BE10.2.1 | T10B11.1.1 | Alkylglycerol monooxygenase; Glyceryl-ether monooxygenase that cleaves the O-alkyl bond of ether lipids; Belongs to the sterol desaturase family. TMEM195 subfamily. | Putative pterin-4-alpha-carbinolamine dehydratase. | 0.809 |
agmo-1 | ptps-1 | BE10.2.1 | B0041.6a.1 | Alkylglycerol monooxygenase; Glyceryl-ether monooxygenase that cleaves the O-alkyl bond of ether lipids; Belongs to the sterol desaturase family. TMEM195 subfamily. | Putative 6-pyruvoyl tetrahydrobiopterin synthase; Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin (By similarity); Belongs to the PTPS family. | 0.665 |
agmo-1 | qdpr-1 | BE10.2.1 | T03F6.1.1 | Alkylglycerol monooxygenase; Glyceryl-ether monooxygenase that cleaves the O-alkyl bond of ether lipids; Belongs to the sterol desaturase family. TMEM195 subfamily. | Quinoid DihydroPteridine Reductase. | 0.766 |
aqp-2 | pcbd-1 | C01G6.1a.3 | T10B11.1.1 | AQuaPorin or aquaglyceroporin related; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Putative pterin-4-alpha-carbinolamine dehydratase. | 0.692 |
cat-2 | dhfr-1 | B0432.5a.1 | C36B1.7.1 | Tyrosine 3-monooxygenase; Involved in the synthesis of catecholamines, such as dopamine. Has a role in serotonin signaling. Required for normal explorative and foraging behavior. | Putative dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity). | 0.906 |
cat-2 | hgo-1 | B0432.5a.1 | W06D4.1.1 | Tyrosine 3-monooxygenase; Involved in the synthesis of catecholamines, such as dopamine. Has a role in serotonin signaling. Required for normal explorative and foraging behavior. | Homogentisate 1,2-dioxygenase. | 0.815 |
cat-2 | pah-1 | B0432.5a.1 | K08F8.4a.1 | Tyrosine 3-monooxygenase; Involved in the synthesis of catecholamines, such as dopamine. Has a role in serotonin signaling. Required for normal explorative and foraging behavior. | Phenylalanine-4-hydroxylase; Catalyzes the hydroxylation of L-phenylalanine to L-tyrosine. Catalyzes the hydroxylation of tryptophan to 5-hydroxy-L-tryptophan. Plays a role in the biosynthesis of a melanin-like cuticle pigment. Belongs to the biopterin-dependent aromatic amino acid hydroxylase family. | 0.918 |
cat-2 | pcbd-1 | B0432.5a.1 | T10B11.1.1 | Tyrosine 3-monooxygenase; Involved in the synthesis of catecholamines, such as dopamine. Has a role in serotonin signaling. Required for normal explorative and foraging behavior. | Putative pterin-4-alpha-carbinolamine dehydratase. | 0.984 |
cat-2 | qdpr-1 | B0432.5a.1 | T03F6.1.1 | Tyrosine 3-monooxygenase; Involved in the synthesis of catecholamines, such as dopamine. Has a role in serotonin signaling. Required for normal explorative and foraging behavior. | Quinoid DihydroPteridine Reductase. | 0.945 |
cat-2 | sup-18 | B0432.5a.1 | C02C2.5.1 | Tyrosine 3-monooxygenase; Involved in the synthesis of catecholamines, such as dopamine. Has a role in serotonin signaling. Required for normal explorative and foraging behavior. | Iodotyrosine dehalogenase 1 homolog; May contribute to coordination of muscle contraction as regulatory subunit of the nonessential sup-9 potassium channel complex. May act downstream of sup-10. | 0.447 |
cat-2 | tph-1 | B0432.5a.1 | ZK1290.2a.1 | Tyrosine 3-monooxygenase; Involved in the synthesis of catecholamines, such as dopamine. Has a role in serotonin signaling. Required for normal explorative and foraging behavior. | BH4_AAA_HYDROXYL_2 domain-containing protein. | 0.923 |
dhfr-1 | cat-2 | C36B1.7.1 | B0432.5a.1 | Putative dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity). | Tyrosine 3-monooxygenase; Involved in the synthesis of catecholamines, such as dopamine. Has a role in serotonin signaling. Required for normal explorative and foraging behavior. | 0.906 |
dhfr-1 | pah-1 | C36B1.7.1 | K08F8.4a.1 | Putative dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity). | Phenylalanine-4-hydroxylase; Catalyzes the hydroxylation of L-phenylalanine to L-tyrosine. Catalyzes the hydroxylation of tryptophan to 5-hydroxy-L-tryptophan. Plays a role in the biosynthesis of a melanin-like cuticle pigment. Belongs to the biopterin-dependent aromatic amino acid hydroxylase family. | 0.906 |
dhfr-1 | pcbd-1 | C36B1.7.1 | T10B11.1.1 | Putative dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity). | Putative pterin-4-alpha-carbinolamine dehydratase. | 0.741 |
dhfr-1 | ptps-1 | C36B1.7.1 | B0041.6a.1 | Putative dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity). | Putative 6-pyruvoyl tetrahydrobiopterin synthase; Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin (By similarity); Belongs to the PTPS family. | 0.640 |
dhfr-1 | qdpr-1 | C36B1.7.1 | T03F6.1.1 | Putative dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity). | Quinoid DihydroPteridine Reductase. | 0.971 |
dhfr-1 | tph-1 | C36B1.7.1 | ZK1290.2a.1 | Putative dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity). | BH4_AAA_HYDROXYL_2 domain-containing protein. | 0.906 |
hgo-1 | cat-2 | W06D4.1.1 | B0432.5a.1 | Homogentisate 1,2-dioxygenase. | Tyrosine 3-monooxygenase; Involved in the synthesis of catecholamines, such as dopamine. Has a role in serotonin signaling. Required for normal explorative and foraging behavior. | 0.815 |
hgo-1 | pah-1 | W06D4.1.1 | K08F8.4a.1 | Homogentisate 1,2-dioxygenase. | Phenylalanine-4-hydroxylase; Catalyzes the hydroxylation of L-phenylalanine to L-tyrosine. Catalyzes the hydroxylation of tryptophan to 5-hydroxy-L-tryptophan. Plays a role in the biosynthesis of a melanin-like cuticle pigment. Belongs to the biopterin-dependent aromatic amino acid hydroxylase family. | 0.815 |