STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tmc-1Transmembrane channel-like protein 1; Sodium-sensor ion channel that acts specifically in salt taste chemosensation. Required for salt-evoked neuronal activity and behavioral avoidance of high concentrations of NaCl. Belongs to the TMC family. (1285 aa)    
Predicted Functional Partners:
calm-1
CALMyrin (Calcium and Integrin Binding protein) homolog.
  
 
 
 0.983
Y39A1C.1
Uncharacterized protein.
    
   0.900
arrd-6
ARRestin Domain protein.
   
   0.805
trp-4
ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family.
   
 
 0.730
mec-10
Degenerin mec-10; Amiloride-sensitive sodium channel subunit required for mechanosensory transduction (touch sensitivity). Negatively regulates the turning step of male mating behavior.
   
  
 0.702
F53B1.2
Sphingomyelin synthase-related 1.
      
 0.694
mec-4
Degenerin mec-4; Probable sodium channel subunit. May be needed for mechanosensory transduction (touch sensitivity). Negatively regulates the turning step of male mating behavior.
   
  
 0.671
deg-1
Degenerin deg-1; Probable sodium channel subunit. Required by a subset of neurons.
      
 0.660
Y17G7B.3
Lactamase_B domain-containing protein.
      
 0.660
nab-1
NeurABin.
   
 
 0.629
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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