STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tag-18Uncharacterized protein. (201 aa)    
Predicted Functional Partners:
ZK1058.9
Uncharacterized protein.
   
    0.512
ZK1321.4
PDZ domain-containing protein.
   
    0.453
R13H4.2
Uncharacterized protein.
   
   
0.442
tnt-2
TropoNin T.
   
    0.431
unc-87
Protein unc-87; Thin filament-associated protein that is implicated in actin bundling and actin filament dynamics. Exhibits F-actin cross-linking activity. Required for the maintenance of sarcomeric actin organization in striated muscles. Competes with unc-60 isoform b for actin binding and protects actin filaments from depolymerization by unc-60, thereby contributing to actin filament stability. Cooperates with myosin to form actomyosin bundles and inhibits actomyosin ATPase activity and actomyosin motility. Might protect the myofilaments from mechanical stress.
   
    0.410
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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