col-141 protein (Caenorhabditis elegans) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

col-141

Col_cuticle_N domain-containing protein. (314 aa)

Predicted Functional Partners:

col-44

0.634

col-139

0.633

dbl-1

0.545

col-165

0.535

adt-2

0.509

col-120

0.503

blmp-1

0.461

C09F9.2

0.406

Your Current Organism:

Caenorhabditis elegans

NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C09F9.2	col-141	C09F9.2.1	T15B7.5.1	Uncharacterized protein.	Col_cuticle_N domain-containing protein.	0.406
adt-2	col-141	F08C6.1a.2	T15B7.5.1	A disintegrin and metalloproteinase with thrombospondin motifs adt-2; Regulates body size probably independently of the TGF beta- like dbl-1 pathway. However, may regulate some dbl-1-mediated transcription. Plays a role in cuticle collagen fibril organization. Required for embryonic development.	Col_cuticle_N domain-containing protein.	0.509
adt-2	dbl-1	F08C6.1a.2	T25F10.2.1	A disintegrin and metalloproteinase with thrombospondin motifs adt-2; Regulates body size probably independently of the TGF beta- like dbl-1 pathway. However, may regulate some dbl-1-mediated transcription. Plays a role in cuticle collagen fibril organization. Required for embryonic development.	TGF_BETA_2 domain-containing protein.	0.683
blmp-1	col-141	F25D7.3a.1	T15B7.5.1	B lymphocyte-induced maturation protein 1 homolog; Transcription factor which binds to enhancer elements in the promoter region of genes. Regulates the expression of the transcription factor bed-3 to control vulval development. Promotes terminal differentiation in the hypodermis and is involved in regulation of gonadal outgrowth and entry into the dauer stage. Regulates the timing of dorsalward migration of the distal tip cells of the hermaphrodite gonad by inhibiting precocious unc-5 and lin-29 expression which in turn prevents early dorsalward turning. Plays a role in male tail tip m [...]	Col_cuticle_N domain-containing protein.	0.461
blmp-1	dbl-1	F25D7.3a.1	T25F10.2.1	B lymphocyte-induced maturation protein 1 homolog; Transcription factor which binds to enhancer elements in the promoter region of genes. Regulates the expression of the transcription factor bed-3 to control vulval development. Promotes terminal differentiation in the hypodermis and is involved in regulation of gonadal outgrowth and entry into the dauer stage. Regulates the timing of dorsalward migration of the distal tip cells of the hermaphrodite gonad by inhibiting precocious unc-5 and lin-29 expression which in turn prevents early dorsalward turning. Plays a role in male tail tip m [...]	TGF_BETA_2 domain-containing protein.	0.413
col-120	col-139	Y11D7A.11.1	F41F3.4.1	Col_cuticle_N domain-containing protein.	Col_cuticle_N domain-containing protein.	0.422
col-120	col-141	Y11D7A.11.1	T15B7.5.1	Col_cuticle_N domain-containing protein.	Col_cuticle_N domain-containing protein.	0.503
col-139	col-120	F41F3.4.1	Y11D7A.11.1	Col_cuticle_N domain-containing protein.	Col_cuticle_N domain-containing protein.	0.422
col-139	col-141	F41F3.4.1	T15B7.5.1	Col_cuticle_N domain-containing protein.	Col_cuticle_N domain-containing protein.	0.633
col-141	C09F9.2	T15B7.5.1	C09F9.2.1	Col_cuticle_N domain-containing protein.	Uncharacterized protein.	0.406
col-141	adt-2	T15B7.5.1	F08C6.1a.2	Col_cuticle_N domain-containing protein.	A disintegrin and metalloproteinase with thrombospondin motifs adt-2; Regulates body size probably independently of the TGF beta- like dbl-1 pathway. However, may regulate some dbl-1-mediated transcription. Plays a role in cuticle collagen fibril organization. Required for embryonic development.	0.509
col-141	blmp-1	T15B7.5.1	F25D7.3a.1	Col_cuticle_N domain-containing protein.	B lymphocyte-induced maturation protein 1 homolog; Transcription factor which binds to enhancer elements in the promoter region of genes. Regulates the expression of the transcription factor bed-3 to control vulval development. Promotes terminal differentiation in the hypodermis and is involved in regulation of gonadal outgrowth and entry into the dauer stage. Regulates the timing of dorsalward migration of the distal tip cells of the hermaphrodite gonad by inhibiting precocious unc-5 and lin-29 expression which in turn prevents early dorsalward turning. Plays a role in male tail tip m [...]	0.461
col-141	col-120	T15B7.5.1	Y11D7A.11.1	Col_cuticle_N domain-containing protein.	Col_cuticle_N domain-containing protein.	0.503
col-141	col-139	T15B7.5.1	F41F3.4.1	Col_cuticle_N domain-containing protein.	Col_cuticle_N domain-containing protein.	0.633
col-141	col-165	T15B7.5.1	F14H12.1.1	Col_cuticle_N domain-containing protein.	Col_cuticle_N domain-containing protein.	0.535
col-141	col-44	T15B7.5.1	F54B11.2.1	Col_cuticle_N domain-containing protein.	Col_cuticle_N domain-containing protein.	0.634
col-141	dbl-1	T15B7.5.1	T25F10.2.1	Col_cuticle_N domain-containing protein.	TGF_BETA_2 domain-containing protein.	0.545
col-165	col-141	F14H12.1.1	T15B7.5.1	Col_cuticle_N domain-containing protein.	Col_cuticle_N domain-containing protein.	0.535
col-44	col-141	F54B11.2.1	T15B7.5.1	Col_cuticle_N domain-containing protein.	Col_cuticle_N domain-containing protein.	0.634
dbl-1	adt-2	T25F10.2.1	F08C6.1a.2	TGF_BETA_2 domain-containing protein.	A disintegrin and metalloproteinase with thrombospondin motifs adt-2; Regulates body size probably independently of the TGF beta- like dbl-1 pathway. However, may regulate some dbl-1-mediated transcription. Plays a role in cuticle collagen fibril organization. Required for embryonic development.	0.683