node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
B0507.1 | Y8A9A.2 | B0507.1.1 | Y8A9A.2.1 | EB domain-containing protein. | Uncharacterized protein. | 0.858 |
B0507.1 | hlh-6 | B0507.1.1 | T15H9.3.1 | EB domain-containing protein. | Helix-loop-helix protein 6; Transcription factor that regulates the development of the g2 pharyngeal gland cells and pharyngeal gland function and thereby is required for feeding. Required for the expression of a number of genes in the pharyngeal gland, possibly by binding to the E box motif (5'-CANNTG-3') in the promoter region of these genes. Positively regulates the expression of genes encoding mucin-like proteins, which lubricate the pharyngeal tract to ensure efficient passage of the bacterial food source. Exhibits pharyngeal gland-specific positive autoregulation activity. | 0.806 |
B0507.1 | phat-1 | B0507.1.1 | C46H11.8.1 | EB domain-containing protein. | PHAryngeal gland Toxin-related. | 0.716 |
B0507.1 | phat-5 | B0507.1.1 | T05B4.11.1 | EB domain-containing protein. | PHAryngeal gland Toxin-related. | 0.716 |
B0507.1 | ztf-2 | B0507.1.1 | F13G3.1.1 | EB domain-containing protein. | C2H2-type domain-containing protein. | 0.906 |
Y76B12C.3 | Y8A9A.2 | Y76B12C.3a.1 | Y8A9A.2.1 | Sep15_SelM domain-containing protein. | Uncharacterized protein. | 0.905 |
Y76B12C.3 | hlh-6 | Y76B12C.3a.1 | T15H9.3.1 | Sep15_SelM domain-containing protein. | Helix-loop-helix protein 6; Transcription factor that regulates the development of the g2 pharyngeal gland cells and pharyngeal gland function and thereby is required for feeding. Required for the expression of a number of genes in the pharyngeal gland, possibly by binding to the E box motif (5'-CANNTG-3') in the promoter region of these genes. Positively regulates the expression of genes encoding mucin-like proteins, which lubricate the pharyngeal tract to ensure efficient passage of the bacterial food source. Exhibits pharyngeal gland-specific positive autoregulation activity. | 0.699 |
Y76B12C.3 | phat-5 | Y76B12C.3a.1 | T05B4.11.1 | Sep15_SelM domain-containing protein. | PHAryngeal gland Toxin-related. | 0.809 |
Y8A9A.2 | B0507.1 | Y8A9A.2.1 | B0507.1.1 | Uncharacterized protein. | EB domain-containing protein. | 0.858 |
Y8A9A.2 | Y76B12C.3 | Y8A9A.2.1 | Y76B12C.3a.1 | Uncharacterized protein. | Sep15_SelM domain-containing protein. | 0.905 |
Y8A9A.2 | hlh-6 | Y8A9A.2.1 | T15H9.3.1 | Uncharacterized protein. | Helix-loop-helix protein 6; Transcription factor that regulates the development of the g2 pharyngeal gland cells and pharyngeal gland function and thereby is required for feeding. Required for the expression of a number of genes in the pharyngeal gland, possibly by binding to the E box motif (5'-CANNTG-3') in the promoter region of these genes. Positively regulates the expression of genes encoding mucin-like proteins, which lubricate the pharyngeal tract to ensure efficient passage of the bacterial food source. Exhibits pharyngeal gland-specific positive autoregulation activity. | 0.760 |
Y8A9A.2 | phat-1 | Y8A9A.2.1 | C46H11.8.1 | Uncharacterized protein. | PHAryngeal gland Toxin-related. | 0.714 |
Y8A9A.2 | phat-5 | Y8A9A.2.1 | T05B4.11.1 | Uncharacterized protein. | PHAryngeal gland Toxin-related. | 0.850 |
ceh-22 | hlh-6 | F29F11.5d.1 | T15H9.3.1 | Homeobox protein ceh-22; Involved in combinatorial activation of gene expression in pharyngeal muscle. Specifically binds a site necessary for activity of the B subelement of myo-2 enhancer. | Helix-loop-helix protein 6; Transcription factor that regulates the development of the g2 pharyngeal gland cells and pharyngeal gland function and thereby is required for feeding. Required for the expression of a number of genes in the pharyngeal gland, possibly by binding to the E box motif (5'-CANNTG-3') in the promoter region of these genes. Positively regulates the expression of genes encoding mucin-like proteins, which lubricate the pharyngeal tract to ensure efficient passage of the bacterial food source. Exhibits pharyngeal gland-specific positive autoregulation activity. | 0.712 |
ceh-22 | pha-4 | F29F11.5d.1 | F38A6.1a.1 | Homeobox protein ceh-22; Involved in combinatorial activation of gene expression in pharyngeal muscle. Specifically binds a site necessary for activity of the B subelement of myo-2 enhancer. | Defective pharyngeal development protein 4; Acts as a transcription factor required for formation of the pharyngeal primordium. Binds to the consensus sequence 5'-T[AG]TT[TG][AG][TC]-3' with variations of the sequence affecting onset of target gene expression. Activates a wide array of pharyngeal genes including ceh-22 and myo-2 and represses ectodermal genes lin-26 and elt-3, ensuring pharyngeal cell fate. Required for recruitment of htz-1 to a subset of pharyngeal promoters to ensure gene activation and also acts synergistically with tbx-2 in pharyngeal development. Acts in the regul [...] | 0.862 |
hlh-2 | hlh-6 | M05B5.5a.1 | T15H9.3.1 | BHLH domain-containing protein. | Helix-loop-helix protein 6; Transcription factor that regulates the development of the g2 pharyngeal gland cells and pharyngeal gland function and thereby is required for feeding. Required for the expression of a number of genes in the pharyngeal gland, possibly by binding to the E box motif (5'-CANNTG-3') in the promoter region of these genes. Positively regulates the expression of genes encoding mucin-like proteins, which lubricate the pharyngeal tract to ensure efficient passage of the bacterial food source. Exhibits pharyngeal gland-specific positive autoregulation activity. | 0.742 |
hlh-6 | B0507.1 | T15H9.3.1 | B0507.1.1 | Helix-loop-helix protein 6; Transcription factor that regulates the development of the g2 pharyngeal gland cells and pharyngeal gland function and thereby is required for feeding. Required for the expression of a number of genes in the pharyngeal gland, possibly by binding to the E box motif (5'-CANNTG-3') in the promoter region of these genes. Positively regulates the expression of genes encoding mucin-like proteins, which lubricate the pharyngeal tract to ensure efficient passage of the bacterial food source. Exhibits pharyngeal gland-specific positive autoregulation activity. | EB domain-containing protein. | 0.806 |
hlh-6 | Y76B12C.3 | T15H9.3.1 | Y76B12C.3a.1 | Helix-loop-helix protein 6; Transcription factor that regulates the development of the g2 pharyngeal gland cells and pharyngeal gland function and thereby is required for feeding. Required for the expression of a number of genes in the pharyngeal gland, possibly by binding to the E box motif (5'-CANNTG-3') in the promoter region of these genes. Positively regulates the expression of genes encoding mucin-like proteins, which lubricate the pharyngeal tract to ensure efficient passage of the bacterial food source. Exhibits pharyngeal gland-specific positive autoregulation activity. | Sep15_SelM domain-containing protein. | 0.699 |
hlh-6 | Y8A9A.2 | T15H9.3.1 | Y8A9A.2.1 | Helix-loop-helix protein 6; Transcription factor that regulates the development of the g2 pharyngeal gland cells and pharyngeal gland function and thereby is required for feeding. Required for the expression of a number of genes in the pharyngeal gland, possibly by binding to the E box motif (5'-CANNTG-3') in the promoter region of these genes. Positively regulates the expression of genes encoding mucin-like proteins, which lubricate the pharyngeal tract to ensure efficient passage of the bacterial food source. Exhibits pharyngeal gland-specific positive autoregulation activity. | Uncharacterized protein. | 0.760 |
hlh-6 | ceh-22 | T15H9.3.1 | F29F11.5d.1 | Helix-loop-helix protein 6; Transcription factor that regulates the development of the g2 pharyngeal gland cells and pharyngeal gland function and thereby is required for feeding. Required for the expression of a number of genes in the pharyngeal gland, possibly by binding to the E box motif (5'-CANNTG-3') in the promoter region of these genes. Positively regulates the expression of genes encoding mucin-like proteins, which lubricate the pharyngeal tract to ensure efficient passage of the bacterial food source. Exhibits pharyngeal gland-specific positive autoregulation activity. | Homeobox protein ceh-22; Involved in combinatorial activation of gene expression in pharyngeal muscle. Specifically binds a site necessary for activity of the B subelement of myo-2 enhancer. | 0.712 |