STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
T22B7.3Uncharacterized protein. (282 aa)    
Predicted Functional Partners:
T05F1.9
Uncharacterized protein.
   
  
 0.961
oatr-1
Probable ornithine aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
  
 0.918
C42D4.3
DB domain-containing protein.
   
  
 0.807
grl-21
Ground-like domain-containing protein.
      
 0.760
C30B5.6
Uncharacterized protein.
      
 0.758
F08F3.4
Epimerase domain-containing protein.
      
 0.758
gpdh-1
Glycerol-3-phosphate dehydrogenase [NAD(+)].
      
 0.668
ttr-15
Transthyretin-like protein 15.
      
 0.614
C09B8.4
Uncharacterized protein.
      
 0.569
asd-2
RNA-binding protein asd-2; RNA-binding protein that binds to the 5'-NACUAAY-N(1,20)- UAAY-3' consensus sequence in pre-mRNA introns to promote alternative splicing. Required for mutually exclusive alternative splicing where it modulates the switch between mutually exclusive exons during pre-mRNA maturation. Involved in muscle-specific gene expression regulating the alternative splicing of genes such as let-2 and unc-60 to ensure that their respective isoforms are expressed in muscle. Promotes the removal of intron 10 from let-2 pre-mRNA to allow for the exclusive expression of the musc [...]
   
  
 0.421
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.