STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gst-23Glutathione S-Transferase. (208 aa)    
Predicted Functional Partners:
prdx-6
Thioredoxin domain-containing protein.
   
 0.831
gst-1
Glutathione S-transferase P; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles (By similarity). Prevents dopaminergic CEP neuron degeneration in response to Mn(2+).
  
0.816
gpx-5
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
   
 
 0.764
gpx-3
Glutathione peroxidase 3; Belongs to the glutathione peroxidase family.
   
 
 0.757
gpx-7
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
   
 
 0.753
W01A11.1
Epoxide hydrolase.
   
 
 0.753
gpx-2
Glutathione peroxidase 2; May constitute a glutathione peroxidase-like protective system against oxidative stresses.
   
 
 0.745
gpx-1
Glutathione peroxidase 1; May constitute a glutathione peroxidase-like protective system against oxidative stresses.
   
 
 0.744
gst-6
Probable glutathione S-transferase 6; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Belongs to the GST superfamily. Sigma family.
  
 
0.729
gsto-2
Probable glutathione transferase omega-2; Exhibits glutathione-dependent thiol transferase activity. Has dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) (By similarity); Belongs to the GST superfamily. Omega family.
   
 
 0.722
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.