STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
T28C12.4Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (658 aa)    
Predicted Functional Partners:
C29F7.2
CHK domain-containing protein.
   
  
 0.809
clec-206
C-type lectin domain-containing protein.
   
  
 0.806
F49F1.7
ShKT domain-containing protein.
   
 
 0.711
dhs-4
DeHydrogenases, Short chain; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
  
 0.700
col-181
Col_cuticle_N domain-containing protein.
    
 
 0.677
K05B2.4
Uncharacterized protein.
   
 
 0.668
kqt-2
Ion_trans domain-containing protein; Belongs to the potassium channel family.
   
  
 0.667
sel-9
Suppressor/enhancer of lin-12 protein 9; May have a role in the negative regulation of lin-12 and glp- 1 transport to the cell surface. May also have a role in a quality control mechanism for endoplasmic reticulum-Golgi transport; the budding of coatomer-coated and other species of coated vesicles, could bind cargo molecules to collect them into budding vesicles. Involved in regulating the expression of proteasomal subunits such as rpt-3 in order to confer resistance to proteasomal dysfunction. Belongs to the EMP24/GP25L family.
      
 0.660
kqt-3
Potassium channel, KvQLT family; Belongs to the potassium channel family.
      
 0.660
K07E3.4
Uncharacterized protein.
   
  
 0.628
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.