STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cah-6Alpha-carbonic anhydrase domain-containing protein; Belongs to the alpha-carbonic anhydrase family. (319 aa)    
Predicted Functional Partners:
bca-1
Beta carbonic anhydrase 1; Reversible hydration of carbon dioxide; Belongs to the beta-class carbonic anhydrase family.
    
 0.986
cah-5
Putative carbonic anhydrase 5; Reversible hydration of carbon dioxide.
  
 
0.944
cah-3
Putative carbonic anhydrase 3; Reversible hydration of carbon dioxide.
  
 
0.942
bca-2
Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.
     
 0.872
Y54E10A.10
Ribosome production factor 2 homolog.
   
 
 0.709
gcy-29
Receptor-type guanylate cyclase gcy-29; Guanylate cyclase involved in the production of the second messenger cGMP (By similarity).
      
 0.660
cah-4
Alpha-carbonic anhydrase domain-containing protein; Belongs to the alpha-carbonic anhydrase family.
  
 
0.658
rrbs-1
Ribosome biogenesis regulatory protein homolog; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family.
   
 
 0.620
Y54H5A.1
WD_REPEATS_REGION domain-containing protein.
   
  
 0.616
rpl-5
60S ribosomal protein L5; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...]
   
 
 0.602
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.