node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
H24G06.1 | mnr-1 | H24G06.1a.1 | W01F3.1a.1 | Uncharacterized protein. | MeNoRin (Dendritic branching protein). | 0.777 |
act-4 | dma-1 | M03F4.2a.1 | T01G9.3.1 | Actin-4; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | LRRCT domain-containing protein. | 0.866 |
act-4 | hpo-30 | M03F4.2a.1 | R04F11.1.1 | Actin-4; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Uncharacterized protein. | 0.751 |
act-4 | kpc-1 | M03F4.2a.1 | F11A6.1a.1 | Actin-4; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Furin-like protease kpc-1; Furin-like protease which cleaves proproteins at the RX(K/R)R consensus motif. During neuronal development, regulates the formation and extension of dendrite branches and cellular positioning of various type of neurons. Promotes the formation, extension and self-avoidance of dendritic branches of PVD and FLP mechanosensory neurons. In PVD neurons, regulates plasma membrane levels of branching receptor dma-1 by targeting it to late endosomes and thus promotes normal dendrite branching and dendrite self-avoidance. Also controls dendrite extension in AIY and D-t [...] | 0.440 |
act-4 | lect-2 | M03F4.2a.1 | K05F1.5.2 | Actin-4; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Peptidase_M23 domain-containing protein. | 0.803 |
act-4 | mnr-1 | M03F4.2a.1 | W01F3.1a.1 | Actin-4; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | MeNoRin (Dendritic branching protein). | 0.816 |
act-4 | tiam-1 | M03F4.2a.1 | C11D9.1.1 | Actin-4; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | DH domain-containing protein. | 0.804 |
bicd-1 | dma-1 | C43G2.2a.1 | T01G9.3.1 | Protein bicaudal D homolog; Part of a complex with dlc-1 and egal-1, which is recruited to the nuclear envelope by unc-83, where in turn, it recruits dynein to the nuclear surface and regulates nuclear migration in hypodermal precursor cells (Probable). Required for the formation of dendritic branches of PVD sensory neurons ; Belongs to the BicD family. | LRRCT domain-containing protein. | 0.551 |
bicd-1 | hpo-30 | C43G2.2a.1 | R04F11.1.1 | Protein bicaudal D homolog; Part of a complex with dlc-1 and egal-1, which is recruited to the nuclear envelope by unc-83, where in turn, it recruits dynein to the nuclear surface and regulates nuclear migration in hypodermal precursor cells (Probable). Required for the formation of dendritic branches of PVD sensory neurons ; Belongs to the BicD family. | Uncharacterized protein. | 0.570 |
bicd-1 | mnr-1 | C43G2.2a.1 | W01F3.1a.1 | Protein bicaudal D homolog; Part of a complex with dlc-1 and egal-1, which is recruited to the nuclear envelope by unc-83, where in turn, it recruits dynein to the nuclear surface and regulates nuclear migration in hypodermal precursor cells (Probable). Required for the formation of dendritic branches of PVD sensory neurons ; Belongs to the BicD family. | MeNoRin (Dendritic branching protein). | 0.623 |
clr-1 | dma-1 | F56D1.4b.1 | T01G9.3.1 | Receptor-type tyrosine-protein phosphatase; Possesses an intrinsic protein tyrosine phosphatase (PTPase) activity. Regulates egl-15 activity which is required for hypodermis-mediated fluid homeostasis and protein degradation in muscle. During the formation of neuromuscular junctions at the larval stage, negatively regulates membrane protrusion from body wall muscles. Plays a role in nicotinic acetylcholine receptor (nAChR)-mediated sensitivity to nicotine. Regulates synaptic levels of nAchR subunit lev-1 in the nerve cord. Promotes the outgrowth of the quaternary dendritic branches of [...] | LRRCT domain-containing protein. | 0.759 |
clr-1 | mnr-1 | F56D1.4b.1 | W01F3.1a.1 | Receptor-type tyrosine-protein phosphatase; Possesses an intrinsic protein tyrosine phosphatase (PTPase) activity. Regulates egl-15 activity which is required for hypodermis-mediated fluid homeostasis and protein degradation in muscle. During the formation of neuromuscular junctions at the larval stage, negatively regulates membrane protrusion from body wall muscles. Plays a role in nicotinic acetylcholine receptor (nAChR)-mediated sensitivity to nicotine. Regulates synaptic levels of nAchR subunit lev-1 in the nerve cord. Promotes the outgrowth of the quaternary dendritic branches of [...] | MeNoRin (Dendritic branching protein). | 0.660 |
clr-1 | sax-7 | F56D1.4b.1 | C18F3.2c.1 | Receptor-type tyrosine-protein phosphatase; Possesses an intrinsic protein tyrosine phosphatase (PTPase) activity. Regulates egl-15 activity which is required for hypodermis-mediated fluid homeostasis and protein degradation in muscle. During the formation of neuromuscular junctions at the larval stage, negatively regulates membrane protrusion from body wall muscles. Plays a role in nicotinic acetylcholine receptor (nAChR)-mediated sensitivity to nicotine. Regulates synaptic levels of nAchR subunit lev-1 in the nerve cord. Promotes the outgrowth of the quaternary dendritic branches of [...] | Fibronectin type-III domain-containing protein. | 0.635 |
dma-1 | act-4 | T01G9.3.1 | M03F4.2a.1 | LRRCT domain-containing protein. | Actin-4; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | 0.866 |
dma-1 | bicd-1 | T01G9.3.1 | C43G2.2a.1 | LRRCT domain-containing protein. | Protein bicaudal D homolog; Part of a complex with dlc-1 and egal-1, which is recruited to the nuclear envelope by unc-83, where in turn, it recruits dynein to the nuclear surface and regulates nuclear migration in hypodermal precursor cells (Probable). Required for the formation of dendritic branches of PVD sensory neurons ; Belongs to the BicD family. | 0.551 |
dma-1 | clr-1 | T01G9.3.1 | F56D1.4b.1 | LRRCT domain-containing protein. | Receptor-type tyrosine-protein phosphatase; Possesses an intrinsic protein tyrosine phosphatase (PTPase) activity. Regulates egl-15 activity which is required for hypodermis-mediated fluid homeostasis and protein degradation in muscle. During the formation of neuromuscular junctions at the larval stage, negatively regulates membrane protrusion from body wall muscles. Plays a role in nicotinic acetylcholine receptor (nAChR)-mediated sensitivity to nicotine. Regulates synaptic levels of nAchR subunit lev-1 in the nerve cord. Promotes the outgrowth of the quaternary dendritic branches of [...] | 0.759 |
dma-1 | hpo-30 | T01G9.3.1 | R04F11.1.1 | LRRCT domain-containing protein. | Uncharacterized protein. | 0.976 |
dma-1 | kpc-1 | T01G9.3.1 | F11A6.1a.1 | LRRCT domain-containing protein. | Furin-like protease kpc-1; Furin-like protease which cleaves proproteins at the RX(K/R)R consensus motif. During neuronal development, regulates the formation and extension of dendrite branches and cellular positioning of various type of neurons. Promotes the formation, extension and self-avoidance of dendritic branches of PVD and FLP mechanosensory neurons. In PVD neurons, regulates plasma membrane levels of branching receptor dma-1 by targeting it to late endosomes and thus promotes normal dendrite branching and dendrite self-avoidance. Also controls dendrite extension in AIY and D-t [...] | 0.783 |
dma-1 | lect-2 | T01G9.3.1 | K05F1.5.2 | LRRCT domain-containing protein. | Peptidase_M23 domain-containing protein. | 0.946 |
dma-1 | mnr-1 | T01G9.3.1 | W01F3.1a.1 | LRRCT domain-containing protein. | MeNoRin (Dendritic branching protein). | 0.985 |