STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W02B8.2Uncharacterized protein. (1256 aa)    
Predicted Functional Partners:
zen-4
Kinesin-like protein.
   
 
 0.624
aspm-1
Calponin-homology (CH) domain-containing protein.
   
  
 0.595
ani-1
Anillin-like protein 1; Required for contractile events in embryos that occur prior to mitosis, such as cortical ruffling and pseudocleavage. Promotes membrane ruffling by organizing cortical patches of septins and myosin II. Not generally required for cytokinesis in mitotic cells. Required for the asymmetric cleavage events that extrude the two polar bodies during oocyte meiosis. Not required for meiotic contractile ring assembly, initiation or closure but is required for the transformation of the contractile ring from a disk above the spindle to a tube around the spindle midzone. Pro [...]
   
 
 0.543
bmk-1
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 
 0.530
ilys-6
Invertebrate-type lysozyme 6; Has bacteriolytic activity against Gram-positive bacteria. Belongs to the glycosyl hydrolase 22 family. Type-I lysozyme subfamily.
   
  
 0.530
icp-1
INCENP_ARK-bind domain-containing protein.
   
 
 0.529
ani-3
Anillin-like protein 3.
   
 
 0.515
ani-2
Anillin-like protein 2; Required to maintain the structure of the rachis, the central cytoplasmic core of the syncytial adult gonad. Failure to maintain the rachis leads to premature dissociation of oocytes and thereby impedes oogenesis.
   
 
 0.506
Y54E5A.7
Uncharacterized protein.
   
 
 0.493
cyk-4
CYtoKinesis defect.
   
 
 0.438
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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