STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W03F9.11Uncharacterized protein. (202 aa)    
Predicted Functional Partners:
ttb-1
Transcription initiation factor IIB; General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II.
      
 0.854
nra-4
Nicotinic receptor-associated protein 4; Involved in the recognition and selection of protein complexes to exit the endoplasmic reticulum (ER). In muscles, regulates levamisole-sensitive nicotinic acetylcholine receptor (L-AChR) subunit composition, possibly by allowing only specific L-AChR subunit combinations to exit the ER. Specifically, may promote the inclusion of alpha subunit unc-38 into and the exclusion of unc-29 from L-AChR. Regulates L- AChR sensitivity to agonists such as nicotine and levamisole at neuro- muscular junctions.
      
 0.850
W03F9.4
Carn_acyltransf domain-containing protein.
      
 0.813
Y69H2.3
Uncharacterized protein.
      
 0.809
flp-34
FMRF-Like Peptide.
   
  
 0.760
W01A8.6
Peptidase_M14 domain-containing protein.
      
 0.746
F53A2.9
Uncharacterized protein.
      
 0.741
let-858
Pre-mRNA-splicing factor CWC22 homolog; Required for pre-mRNA splicing and for exon-junction complex (EJC) assembly. Hinders EIF4A3 from non-specifically binding RNA and escorts it to the splicing machinery to promote EJC assembly on mature mRNAs. Through its role in EJC assembly, required for nonsense-mediated mRNA decay (By similarity). Required for early embryogenesis and tissue differentiation; Belongs to the CWC22 family.
      
 0.465
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.