STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
app-1Xaa-Pro aminopeptidase app-1; Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro. Has activity towards the flp-9 neuropeptide KPSFVRF- amide. (616 aa)    
Predicted Functional Partners:
W03G9.2
Uncharacterized protein.
 
  
 0.803
nas-28
Zinc metalloproteinase nas-28; Metalloprotease.
   
  
 0.709
Y48G1C.1
Uncharacterized protein.
   
  
 0.703
aps-3
Clat_adaptor_s domain-containing protein.
 
 
  
 0.697
nas-11
Zinc metalloproteinase nas-11; Metalloprotease.
   
  
 0.696
C08H9.1
Serine carboxypeptidase ctsa-3.2; Belongs to the peptidase S10 family.
   
 
 0.689
Y16B4A.2
Carboxypeptidase; Belongs to the peptidase S10 family.
   
 
 0.689
gcna-1
SprT-like domain-containing protein.
   
  
 0.686
dnpp-1
Aspartyl aminopeptidase; Aminopeptidase with specificity towards an acidic amino acid at the N-terminus. Plays a role in membrane trafficking and is specifically involved in the recycling and degradation of endocytic cargo.
  
 
 0.638
rpl-7
60S ribosomal protein L7; Binds to G-rich structures in 28S rRNA and in mRNAs. Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs (By similarity).
 
 
    0.622
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.