STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nhl-3B box-type domain-containing protein. (698 aa)    
Predicted Functional Partners:
C28G1.6
RING-type domain-containing protein.
    
 
 0.762
F43C11.8
RING-type domain-containing protein.
    
 
 0.762
ZK1240.1
RING-type domain-containing protein.
   
 
 0.762
ZK1240.3
RING-type domain-containing protein.
    
 
 0.762
ZK1240.6
RING-type domain-containing protein.
    
 
 0.762
nhl-2
NHL (Ring finger b-box coiled coil) domain containing.
      
 0.746
K09F6.7
RING-type domain-containing protein.
    
 
 0.702
ZK1240.2
RING-type domain-containing protein.
    
 
 0.667
ubc-22
UBiquitin Conjugating enzyme.
   
 
 0.602
rnf-113
Probable E3 ubiquitin-protein ligase rnf113; May function as E3 ubiquitin-protein ligase that catalyzes the transfer of ubiquitin onto target proteins. May play a role in DNA repair via its role in the synthesis of 'Lys-63'-linked polyubiquitin chains that recruit proteins involved in repair to sites of DNA damage by alkylating agents.
      
 0.525
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.