STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ceh-32Homeobox protein ceh-32; Plays a role in head morphogenesis, expression is regulated by vab-3. (439 aa)    
Predicted Functional Partners:
eya-1
Eyes absent homolog 1; Tyrosine protein phosphatase (By similarity). Acts probably as a transcription regulator in the embryonic and postembryonic development of several tissues including pharynx, vulva and gonads. Required for the development of anterior tissues during late embryogenesis. Together with ceh-34, required to specify the coelomocyte fate in embryonic and postembryonic precursors. In the anterior part of the embryo, prevents apoptosis in cells that are not fated to die. Together with ceh-34 activates proapoptotic factor egl-1 expression to promote motor neuron M4 sister ce [...]
   
 
 0.934
vab-3
Homeobox domain-containing protein.
   
 
 0.902
ceh-43
Homeobox protein ceh-43; Required for development of the anterior hypdermis during embryonic morphogenesis for cell adhesion; also affects embryonic and larval viability.
  
  
 0.892
ceh-8
Homeobox protein ceh-8.
   
 
 0.854
ceh-10
Homeobox protein ceh-10; Required for larval development and for cell fate specification and migration of CAN neurons.
   
  
 0.725
egl-38
Paired domain-containing protein.
  
  
 0.712
ceh-5
Homeobox protein ceh-5.
   
 
 0.695
pax-2
Paired domain-containing protein.
  
   
 0.691
ceh-6
Homeobox protein ceh-6; Vital for embryonic development and essential for the proper function of the excretory cell. Required for the transdifferentiation of the Y rectal epithelial cell to the PDA motor neuron during larval development.
  
  
 0.669
srab-4
Serpentine Receptor, class AB (Class A-like).
      
 0.667
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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