STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
zmp-4ZnMc domain-containing protein. (472 aa)    
Predicted Functional Partners:
C28F5.4
Putative zinc protease C28F5.4; Belongs to the peptidase M16 family.
      
 0.759
nep-1
Neprilysin-1; Probable cell surface protease. Required to control the neuronal innervation of pharyngeal pumping. Belongs to the peptidase M13 family.
      
 0.758
nep-11
Neprilysin-11; Probable cell surface protease; Belongs to the peptidase M13 family.
   
  
 0.708
nep-2
Neprilysin-2; Required for olfactory plasticity, which is the change from positive chemotaxis to dispersal after prolonged exposure to an odorant. Thought to antagonise snet-1 by degrading excess snet-1 peptides and thus enabling olfactory plasticity.
   
  
 0.708
dpy-31
Zinc metalloproteinase dpy-31; Metalloprotease which cleaves the carboxyl terminus of procollagens, such as sqt-3, to mature collagens (By similarity). Involved in cuticular collagen maturation.
   
 
 0.707
nep-21
Neprilysin-21; Probable cell surface protease.
      
 0.700
ppgn-1
AAA domain-containing protein.
   
  
 0.700
col-130
Col_cuticle_N domain-containing protein.
   
 
 0.675
F32H5.1
Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.
   
  
 0.566
Y43F4A.1
Leishmanolysin-like peptidase; Essential for the coordination of mitotic progression, and also plays a role in cell migration.
      
 0.549
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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