STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
maea-1MAEA (MAcrophage Erythroblast Attacher protein) homolog. (428 aa)    
Predicted Functional Partners:
T07D1.2
Zf-RING_UBOX domain-containing protein.
   
 0.982
Y54E5A.7
Uncharacterized protein.
   
 
 0.964
tag-304
Uncharacterized protein.
   
 
 0.962
Y39H10A.6
WD_REPEATS_REGION domain-containing protein.
    
 0.912
fbp-1
FBPase domain-containing protein; Belongs to the FBPase class 1 family.
   
 
 0.588
atg-4.1
Cysteine protease atg-4.1; Cysteine protease required for autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins lgg-1, to reveal a C-terminal glycine (Probable). Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy (Probable). Its cleavage activity is functionally redundant to atg-4.2, but it cleaves lgg-1 precursors more efficiently than atg-4.2 (Probable). Acts redundantly with atg-4.2 to promote the lgg-1 delipidation to release the protein fro [...]
   
    0.470
B0546.4
Protein yippee-like B0546.4.
   
 
 0.415
psmd-9
Probable 26S proteasome non-ATPase regulatory subunit 9; Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the 19S regulatory complex (RC); Belongs to the proteasome subunit p27 family.
   
  
 0.411
B0546.3
Yippee domain-containing protein.
   
 
 0.407
F37A8.5
Protein yippee-like F37A8.5; Belongs to the yippee family.
   
 
 0.407
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.