Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| F56E10.1 | mef-2 | F56E10.1b.1 | W10D5.1.1 | Uncharacterized protein. | MADS-box domain-containing protein. | 0.716 |
| hda-4 | kin-29 | C10E2.3a.1 | F58H12.1.1 | Histone deacetylase 4; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). May be involved in muscle development. | Serine/threonine-protein kinase kin-29; Regulates chemoreceptor expression by phosphorylating the hda-4 class II histone deacetylase (HDAC) and inhibiting the gene repression functions of hda-4 and the mef-2 transcription factor, enabling the correct sensing and transduction of food signals. Role in determining body size, the dauer decision and serotonin-mediated egg laying. May modulate the Sma/Mab pathway and regulates development in the later larval stages. | 0.883 |
| hda-4 | mef-2 | C10E2.3a.1 | W10D5.1.1 | Histone deacetylase 4; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). May be involved in muscle development. | MADS-box domain-containing protein. | 0.924 |
| hlh-8 | mef-2 | C02B8.4.1 | W10D5.1.1 | Twist-related protein; Acts as a transcriptional regulator. Involved in postembryonic mesodermal cell fate specification. Activates ceh-24 and egl-15 during mesodermal patterning. | MADS-box domain-containing protein. | 0.625 |
| kin-29 | hda-4 | F58H12.1.1 | C10E2.3a.1 | Serine/threonine-protein kinase kin-29; Regulates chemoreceptor expression by phosphorylating the hda-4 class II histone deacetylase (HDAC) and inhibiting the gene repression functions of hda-4 and the mef-2 transcription factor, enabling the correct sensing and transduction of food signals. Role in determining body size, the dauer decision and serotonin-mediated egg laying. May modulate the Sma/Mab pathway and regulates development in the later larval stages. | Histone deacetylase 4; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). May be involved in muscle development. | 0.883 |
| kin-29 | mef-2 | F58H12.1.1 | W10D5.1.1 | Serine/threonine-protein kinase kin-29; Regulates chemoreceptor expression by phosphorylating the hda-4 class II histone deacetylase (HDAC) and inhibiting the gene repression functions of hda-4 and the mef-2 transcription factor, enabling the correct sensing and transduction of food signals. Role in determining body size, the dauer decision and serotonin-mediated egg laying. May modulate the Sma/Mab pathway and regulates development in the later larval stages. | MADS-box domain-containing protein. | 0.840 |
| kin-29 | srh-234 | F58H12.1.1 | F07C4.14.1 | Serine/threonine-protein kinase kin-29; Regulates chemoreceptor expression by phosphorylating the hda-4 class II histone deacetylase (HDAC) and inhibiting the gene repression functions of hda-4 and the mef-2 transcription factor, enabling the correct sensing and transduction of food signals. Role in determining body size, the dauer decision and serotonin-mediated egg laying. May modulate the Sma/Mab pathway and regulates development in the later larval stages. | Serpentine Receptor, class H. | 0.660 |
| kin-32 | mef-2 | C30F8.4a.1 | W10D5.1.1 | Inactive tyrosine-protein kinase kin-32; Has apparently no tyrosine kinase activity in vitro when expressed in mammalian cells; Belongs to the protein kinase superfamily. Tyr protein kinase family. FAK subfamily. | MADS-box domain-containing protein. | 0.625 |
| mef-2 | F56E10.1 | W10D5.1.1 | F56E10.1b.1 | MADS-box domain-containing protein. | Uncharacterized protein. | 0.716 |
| mef-2 | hda-4 | W10D5.1.1 | C10E2.3a.1 | MADS-box domain-containing protein. | Histone deacetylase 4; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). May be involved in muscle development. | 0.924 |
| mef-2 | hlh-8 | W10D5.1.1 | C02B8.4.1 | MADS-box domain-containing protein. | Twist-related protein; Acts as a transcriptional regulator. Involved in postembryonic mesodermal cell fate specification. Activates ceh-24 and egl-15 during mesodermal patterning. | 0.625 |
| mef-2 | kin-29 | W10D5.1.1 | F58H12.1.1 | MADS-box domain-containing protein. | Serine/threonine-protein kinase kin-29; Regulates chemoreceptor expression by phosphorylating the hda-4 class II histone deacetylase (HDAC) and inhibiting the gene repression functions of hda-4 and the mef-2 transcription factor, enabling the correct sensing and transduction of food signals. Role in determining body size, the dauer decision and serotonin-mediated egg laying. May modulate the Sma/Mab pathway and regulates development in the later larval stages. | 0.840 |
| mef-2 | kin-32 | W10D5.1.1 | C30F8.4a.1 | MADS-box domain-containing protein. | Inactive tyrosine-protein kinase kin-32; Has apparently no tyrosine kinase activity in vitro when expressed in mammalian cells; Belongs to the protein kinase superfamily. Tyr protein kinase family. FAK subfamily. | 0.625 |
| mef-2 | pmk-1 | W10D5.1.1 | B0218.3.1 | MADS-box domain-containing protein. | Mitogen-activated protein kinase pmk-1; Serine/threonine kinase which responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating downstream targets. Phosphorylates snk-1 which probably regulates skn-1 nuclear translocation in response to oxidative stress. Probably by activating skn-1, involved in the up- regulation of gcs-1 and glutathione-S-transferase gst-4 expression upon bacteria infection. Up-regulates expression of gcs-1 in intestinal cells upon arsenite treatment. Functions downstream of the MAPKK sek-1 and the MAPKKK nsy-1 as the MAP kinase [...] | 0.839 |
| mef-2 | pmk-2 | W10D5.1.1 | F42G8.3a.1 | MADS-box domain-containing protein. | Mitogen-activated protein kinase pmk-2; Responds to activation by environmental stress and pro- inflammatory cytokines by phosphorylating downstream targets. | 0.839 |
| mef-2 | pmk-3 | W10D5.1.1 | F42G8.4a.1 | MADS-box domain-containing protein. | Mitogen-activated protein kinase pmk-3; Responds to activation by environmental stress and pro- inflammatory cytokines by phosphorylating downstream targets. Involved in axon regeneration after injury, probably downstream of dlk-1 and mkk-4 and upstream of mak-2. May phosphorylate mak-2. Plays a role in cilium length regulation, possibly by reducing rab-5 mediated endocytosis. Plays a role in the formation of muscle connections, also called muscle arm extensions, between the body wall and the motor axons in the dorsal and ventral cord. | 0.841 |
| mef-2 | srh-234 | W10D5.1.1 | F07C4.14.1 | MADS-box domain-containing protein. | Serpentine Receptor, class H. | 0.759 |
| mef-2 | trt-1 | W10D5.1.1 | DY3.4a.2 | MADS-box domain-containing protein. | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. | 0.672 |
| pmk-1 | mef-2 | B0218.3.1 | W10D5.1.1 | Mitogen-activated protein kinase pmk-1; Serine/threonine kinase which responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating downstream targets. Phosphorylates snk-1 which probably regulates skn-1 nuclear translocation in response to oxidative stress. Probably by activating skn-1, involved in the up- regulation of gcs-1 and glutathione-S-transferase gst-4 expression upon bacteria infection. Up-regulates expression of gcs-1 in intestinal cells upon arsenite treatment. Functions downstream of the MAPKK sek-1 and the MAPKKK nsy-1 as the MAP kinase [...] | MADS-box domain-containing protein. | 0.839 |
| pmk-1 | pmk-2 | B0218.3.1 | F42G8.3a.1 | Mitogen-activated protein kinase pmk-1; Serine/threonine kinase which responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating downstream targets. Phosphorylates snk-1 which probably regulates skn-1 nuclear translocation in response to oxidative stress. Probably by activating skn-1, involved in the up- regulation of gcs-1 and glutathione-S-transferase gst-4 expression upon bacteria infection. Up-regulates expression of gcs-1 in intestinal cells upon arsenite treatment. Functions downstream of the MAPKK sek-1 and the MAPKKK nsy-1 as the MAP kinase [...] | Mitogen-activated protein kinase pmk-2; Responds to activation by environmental stress and pro- inflammatory cytokines by phosphorylating downstream targets. | 0.908 |
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