node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
czw-1 | sec-20 | F20D12.4.2 | F40G9.1.1 | Centromere/kinetochore protein zw10 homolog; Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and mdf-1-mdf-2 complexes onto kinetochores. Its function related to the spindle assembly machinery and kinetochore-microtubule attachments likely depends on its association in the mitotic RZZ complex. The RZZ complex recruits the spindly-like protein spdl-1 to kinetochores. To prevent irregular chromosome segregation, the complex also inhibits the attachment of the kinetochore-associated NDC8 [...] | Yeast SEC homolog; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. | 0.803 |
czw-1 | sec-22 | F20D12.4.2 | F55A4.1.1 | Centromere/kinetochore protein zw10 homolog; Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and mdf-1-mdf-2 complexes onto kinetochores. Its function related to the spindle assembly machinery and kinetochore-microtubule attachments likely depends on its association in the mitotic RZZ complex. The RZZ complex recruits the spindly-like protein spdl-1 to kinetochores. To prevent irregular chromosome segregation, the complex also inhibits the attachment of the kinetochore-associated NDC8 [...] | Yeast SEC homolog; Belongs to the synaptobrevin family. | 0.938 |
czw-1 | smgl-1 | F20D12.4.2 | F20G4.1.1 | Centromere/kinetochore protein zw10 homolog; Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and mdf-1-mdf-2 complexes onto kinetochores. Its function related to the spindle assembly machinery and kinetochore-microtubule attachments likely depends on its association in the mitotic RZZ complex. The RZZ complex recruits the spindly-like protein spdl-1 to kinetochores. To prevent irregular chromosome segregation, the complex also inhibits the attachment of the kinetochore-associated NDC8 [...] | Uncharacterized protein. | 0.999 |
czw-1 | syx-18 | F20D12.4.2 | T10H9.3.1 | Centromere/kinetochore protein zw10 homolog; Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and mdf-1-mdf-2 complexes onto kinetochores. Its function related to the spindle assembly machinery and kinetochore-microtubule attachments likely depends on its association in the mitotic RZZ complex. The RZZ complex recruits the spindly-like protein spdl-1 to kinetochores. To prevent irregular chromosome segregation, the complex also inhibits the attachment of the kinetochore-associated NDC8 [...] | t-SNARE coiled-coil homology domain-containing protein. | 0.996 |
czw-1 | syx-5 | F20D12.4.2 | F55A11.2.1 | Centromere/kinetochore protein zw10 homolog; Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and mdf-1-mdf-2 complexes onto kinetochores. Its function related to the spindle assembly machinery and kinetochore-microtubule attachments likely depends on its association in the mitotic RZZ complex. The RZZ complex recruits the spindly-like protein spdl-1 to kinetochores. To prevent irregular chromosome segregation, the complex also inhibits the attachment of the kinetochore-associated NDC8 [...] | Putative syntaxin-5; Potentially involved in docking of synaptic vesicles at presynaptic active zones; Belongs to the syntaxin family. | 0.500 |
czw-1 | use-1 | F20D12.4.2 | Y110A7A.11.1 | Centromere/kinetochore protein zw10 homolog; Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and mdf-1-mdf-2 complexes onto kinetochores. Its function related to the spindle assembly machinery and kinetochore-microtubule attachments likely depends on its association in the mitotic RZZ complex. The RZZ complex recruits the spindly-like protein spdl-1 to kinetochores. To prevent irregular chromosome segregation, the complex also inhibits the attachment of the kinetochore-associated NDC8 [...] | Vesicle transport protein USE1; SNARE that may be involved in targeting and fusion of Golgi- derived retrograde transport vesicles with the ER; Belongs to the USE1 family. | 0.969 |
czw-1 | ykt-6 | F20D12.4.2 | B0361.10.1 | Centromere/kinetochore protein zw10 homolog; Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and mdf-1-mdf-2 complexes onto kinetochores. Its function related to the spindle assembly machinery and kinetochore-microtubule attachments likely depends on its association in the mitotic RZZ complex. The RZZ complex recruits the spindly-like protein spdl-1 to kinetochores. To prevent irregular chromosome segregation, the complex also inhibits the attachment of the kinetochore-associated NDC8 [...] | YKT6 (Yeast v-SNARE) homolog; Belongs to the synaptobrevin family. | 0.407 |
memb-1 | memb-2 | B0272.2.1 | M03E7.5.3 | Golgi SNAP receptor complex member 2 homolog memb-1; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. | Golgi SNAP receptor complex member 2; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. | 0.919 |
memb-1 | nbet-1 | B0272.2.1 | Y59E9AL.7.1 | Golgi SNAP receptor complex member 2 homolog memb-1; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. | t-SNARE coiled-coil homology domain-containing protein. | 0.998 |
memb-1 | sec-20 | B0272.2.1 | F40G9.1.1 | Golgi SNAP receptor complex member 2 homolog memb-1; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. | Yeast SEC homolog; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. | 0.927 |
memb-1 | sec-22 | B0272.2.1 | F55A4.1.1 | Golgi SNAP receptor complex member 2 homolog memb-1; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. | Yeast SEC homolog; Belongs to the synaptobrevin family. | 0.994 |
memb-1 | syx-18 | B0272.2.1 | T10H9.3.1 | Golgi SNAP receptor complex member 2 homolog memb-1; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. | t-SNARE coiled-coil homology domain-containing protein. | 0.740 |
memb-1 | syx-5 | B0272.2.1 | F55A11.2.1 | Golgi SNAP receptor complex member 2 homolog memb-1; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. | Putative syntaxin-5; Potentially involved in docking of synaptic vesicles at presynaptic active zones; Belongs to the syntaxin family. | 0.992 |
memb-1 | use-1 | B0272.2.1 | Y110A7A.11.1 | Golgi SNAP receptor complex member 2 homolog memb-1; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. | Vesicle transport protein USE1; SNARE that may be involved in targeting and fusion of Golgi- derived retrograde transport vesicles with the ER; Belongs to the USE1 family. | 0.961 |
memb-1 | ykt-6 | B0272.2.1 | B0361.10.1 | Golgi SNAP receptor complex member 2 homolog memb-1; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. | YKT6 (Yeast v-SNARE) homolog; Belongs to the synaptobrevin family. | 0.979 |
memb-2 | memb-1 | M03E7.5.3 | B0272.2.1 | Golgi SNAP receptor complex member 2; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. | Golgi SNAP receptor complex member 2 homolog memb-1; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. | 0.919 |
memb-2 | nbet-1 | M03E7.5.3 | Y59E9AL.7.1 | Golgi SNAP receptor complex member 2; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. | t-SNARE coiled-coil homology domain-containing protein. | 0.998 |
memb-2 | sec-20 | M03E7.5.3 | F40G9.1.1 | Golgi SNAP receptor complex member 2; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. | Yeast SEC homolog; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. | 0.927 |
memb-2 | sec-22 | M03E7.5.3 | F55A4.1.1 | Golgi SNAP receptor complex member 2; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. | Yeast SEC homolog; Belongs to the synaptobrevin family. | 0.993 |
memb-2 | syx-18 | M03E7.5.3 | T10H9.3.1 | Golgi SNAP receptor complex member 2; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. | t-SNARE coiled-coil homology domain-containing protein. | 0.758 |