STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Y17G7B.18Probable RNA methyltransferase Y17G7B.18; Probable RNA methyltransferase; Belongs to the methyltransferase superfamily. (381 aa)    
Predicted Functional Partners:
cdk-9
Probable cyclin-dependent kinase 9; Essential member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD (C- terminal domain) of the large subunit of RNA polymerase II (RNAP II) and spt-5.
   
 
 0.919
M02B7.7
Uncharacterized protein.
   
   0.857
Y48C3A.18
YrdC-like domain-containing protein.
   
 
 0.815
Y106G6H.6
Uncharacterized protein.
   
  
 0.811
Y17G7B.20
Uncharacterized protein.
   
  
 0.809
Y39E4B.6
Uncharacterized protein.
    
 
 0.809
F25B5.3
Putative cytosolic 5'-nucleotidase 3.
   
  
 0.808
xbx-6
X-BoX promoter element regulated; Belongs to the BI1 family.
      
 0.807
Y41D4A.6
Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the amidase family. GatA subfamily.
      
 0.759
sart-3
SART-3/p110 homolog.
   
 
 0.742
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.