STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Y18H1A.4Uncharacterized protein. (220 aa)    
Predicted Functional Partners:
gpi-1
Glucose-6-phosphate isomerase; Belongs to the GPI family.
    
 0.542
mel-32
Serine hydroxymethyltransferase; Interconversion of serine and glycine; Belongs to the SHMT family.
    
 0.539
fbp-1
FBPase domain-containing protein; Belongs to the FBPase class 1 family.
   
 
 0.533
enol-1
Enolase; Belongs to the enolase family.
  
 
 0.531
pgk-1
Probable phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
  
 
 0.528
tkt-1
Transket_pyr domain-containing protein.
  
 
 0.526
F26H9.5
Probable phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.
    
 0.524
tpi-1
Triosephosphate isomerase; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.
  
 
 0.507
ssp-9
Sperm-specific class P protein 9/11.
   
 0.499
pfk-1.2
ATP-dependent 6-phosphofructokinase 2; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
   
 0.480
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.