node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cosa-1 | him-14 | Y71H2AM.7.1 | ZK1127.11.1 | CrossOver Site Associated. | MutS protein homolog him-14; Required during the pachytene stage of meiotic prophase for the formation of crossovers between homologous chromosomes. Not needed for pairing or synapsis. May promote crossing over by interfering with Holliday junction branch migration. Has no apparent role in DNA mismatch repair. | 0.887 |
cosa-1 | him-6 | Y71H2AM.7.1 | T04A11.6.1 | CrossOver Site Associated. | Bloom syndrome protein homolog; Participates in DNA replication and repair (By similarity). Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction (By similarity). Negatively regulates sister chromatid exchange (SCE) ; Belongs to the helicase family. RecQ subfamily. | 0.711 |
cosa-1 | rec-1 | Y71H2AM.7.1 | Y18H1A.7a.1 | CrossOver Site Associated. | Uncharacterized protein. | 0.407 |
cosa-1 | rmh-1 | Y71H2AM.7.1 | M01E11.3.1 | CrossOver Site Associated. | DUF1767 domain-containing protein. | 0.856 |
cosa-1 | slx-1 | Y71H2AM.7.1 | F56A3.2.1 | CrossOver Site Associated. | Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA (Potential). Has a preference for replication forks over 5' flap structures or Holliday junctions and shows much lower activity toward 3' flap structures. Required for proper crossover distribution through inhibition of crossover formation at the c [...] | 0.548 |
cosa-1 | spo-11 | Y71H2AM.7.1 | T05E11.4a.1 | CrossOver Site Associated. | Meiotic recombination protein spo-11; Required for meiotic recombination. Mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. | 0.923 |
cosa-1 | xnd-1 | Y71H2AM.7.1 | C05D2.5.1 | CrossOver Site Associated. | X chromosome NonDisjunction factor. | 0.504 |
cosa-1 | zhp-4 | Y71H2AM.7.1 | Y39B6A.16.1 | CrossOver Site Associated. | Zip (Yeast meiotic zipper) Homologous Protein. | 0.792 |
hgap-1 | rec-1 | Y18H1A.3e.1 | Y18H1A.7a.1 | Rap-GAP domain-containing protein. | Uncharacterized protein. | 0.697 |
him-14 | cosa-1 | ZK1127.11.1 | Y71H2AM.7.1 | MutS protein homolog him-14; Required during the pachytene stage of meiotic prophase for the formation of crossovers between homologous chromosomes. Not needed for pairing or synapsis. May promote crossing over by interfering with Holliday junction branch migration. Has no apparent role in DNA mismatch repair. | CrossOver Site Associated. | 0.887 |
him-14 | him-6 | ZK1127.11.1 | T04A11.6.1 | MutS protein homolog him-14; Required during the pachytene stage of meiotic prophase for the formation of crossovers between homologous chromosomes. Not needed for pairing or synapsis. May promote crossing over by interfering with Holliday junction branch migration. Has no apparent role in DNA mismatch repair. | Bloom syndrome protein homolog; Participates in DNA replication and repair (By similarity). Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction (By similarity). Negatively regulates sister chromatid exchange (SCE) ; Belongs to the helicase family. RecQ subfamily. | 0.902 |
him-14 | rec-1 | ZK1127.11.1 | Y18H1A.7a.1 | MutS protein homolog him-14; Required during the pachytene stage of meiotic prophase for the formation of crossovers between homologous chromosomes. Not needed for pairing or synapsis. May promote crossing over by interfering with Holliday junction branch migration. Has no apparent role in DNA mismatch repair. | Uncharacterized protein. | 0.606 |
him-14 | rmh-1 | ZK1127.11.1 | M01E11.3.1 | MutS protein homolog him-14; Required during the pachytene stage of meiotic prophase for the formation of crossovers between homologous chromosomes. Not needed for pairing or synapsis. May promote crossing over by interfering with Holliday junction branch migration. Has no apparent role in DNA mismatch repair. | DUF1767 domain-containing protein. | 0.847 |
him-14 | slx-1 | ZK1127.11.1 | F56A3.2.1 | MutS protein homolog him-14; Required during the pachytene stage of meiotic prophase for the formation of crossovers between homologous chromosomes. Not needed for pairing or synapsis. May promote crossing over by interfering with Holliday junction branch migration. Has no apparent role in DNA mismatch repair. | Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA (Potential). Has a preference for replication forks over 5' flap structures or Holliday junctions and shows much lower activity toward 3' flap structures. Required for proper crossover distribution through inhibition of crossover formation at the c [...] | 0.863 |
him-14 | spo-11 | ZK1127.11.1 | T05E11.4a.1 | MutS protein homolog him-14; Required during the pachytene stage of meiotic prophase for the formation of crossovers between homologous chromosomes. Not needed for pairing or synapsis. May promote crossing over by interfering with Holliday junction branch migration. Has no apparent role in DNA mismatch repair. | Meiotic recombination protein spo-11; Required for meiotic recombination. Mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. | 0.991 |
him-14 | xnd-1 | ZK1127.11.1 | C05D2.5.1 | MutS protein homolog him-14; Required during the pachytene stage of meiotic prophase for the formation of crossovers between homologous chromosomes. Not needed for pairing or synapsis. May promote crossing over by interfering with Holliday junction branch migration. Has no apparent role in DNA mismatch repair. | X chromosome NonDisjunction factor. | 0.471 |
him-14 | zhp-4 | ZK1127.11.1 | Y39B6A.16.1 | MutS protein homolog him-14; Required during the pachytene stage of meiotic prophase for the formation of crossovers between homologous chromosomes. Not needed for pairing or synapsis. May promote crossing over by interfering with Holliday junction branch migration. Has no apparent role in DNA mismatch repair. | Zip (Yeast meiotic zipper) Homologous Protein. | 0.410 |
him-6 | cosa-1 | T04A11.6.1 | Y71H2AM.7.1 | Bloom syndrome protein homolog; Participates in DNA replication and repair (By similarity). Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction (By similarity). Negatively regulates sister chromatid exchange (SCE) ; Belongs to the helicase family. RecQ subfamily. | CrossOver Site Associated. | 0.711 |
him-6 | him-14 | T04A11.6.1 | ZK1127.11.1 | Bloom syndrome protein homolog; Participates in DNA replication and repair (By similarity). Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction (By similarity). Negatively regulates sister chromatid exchange (SCE) ; Belongs to the helicase family. RecQ subfamily. | MutS protein homolog him-14; Required during the pachytene stage of meiotic prophase for the formation of crossovers between homologous chromosomes. Not needed for pairing or synapsis. May promote crossing over by interfering with Holliday junction branch migration. Has no apparent role in DNA mismatch repair. | 0.902 |
him-6 | rec-1 | T04A11.6.1 | Y18H1A.7a.1 | Bloom syndrome protein homolog; Participates in DNA replication and repair (By similarity). Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction (By similarity). Negatively regulates sister chromatid exchange (SCE) ; Belongs to the helicase family. RecQ subfamily. | Uncharacterized protein. | 0.547 |