STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Y23H5A.2Uncharacterized protein. (197 aa)    
Predicted Functional Partners:
smu-2
Smu-2 suppressor of mec-8 and unc-52 protein; Auxiliary spliceosomal protein that regulates selection of alternative splice sites in a small set of target pre-mRNA species (Probable). Selectively regulates alternative splicing of unc-52 exon 17. Thus, smu-2 mutants selectively suppress the effects of unc-52 nonsense mutations in exon 17 by promoting the accumulation of unc-52 isoforms that lack exon 17. In contrast, smu-2 mutants do not suppress the effects of an unc-52 mutation that affects the 5' splice site of exon 16. Required for normal accumulation of smu-1. Belongs to the RED family.
   
    0.555
let-504
Nkap_C domain-containing protein.
   
    0.553
C24D10.4
Uncharacterized protein.
   
    0.548
Y104H12D.2
Uncharacterized protein.
   
    0.547
F54F2.7
Uncharacterized protein F54F2.7.
   
    0.543
C09H10.5
Uncharacterized protein.
   
    0.538
prp-38
Yeast PRP (Splicing factor) related.
   
    0.538
ubxn-1
UBX domain-containing protein 1; Ubiquitin-binding protein which acts as an adapter for ATPase cdc-48.1 and/or cdc-48.2, conferring substrate specificity. Together with ubxn-2 and ubxn-3, plays a role in hermaphrodite spermatogenesis probably by promoting the degradation of sex determination terminal factor tra-1.
   
    0.538
mrpl-2
Ribosomal_L2_C domain-containing protein.
   
    0.538
K10D2.5
Uncharacterized protein K10D2.5.
   
    0.538
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.