STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Y38C1AA.1PlsC domain-containing protein. (390 aa)    
Predicted Functional Partners:
grld-1
Glutamate Receptor Level Decreased.
   
  
 0.913
frm-1
FERM domain-containing protein.
    
 
 0.704
rpn-6.1
Probable 26S proteasome regulatory subunit rpn-6.1; Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, rpn-6.1 is required for proteasome assembly. Plays a key role in increased proteasome activity in response to proteotoxic stress: induced by daf-16, promoting enhanced assembly of the 26S proteasome and higher proteasome activity, leading to extended lifespan.
 
      0.631
prdx-6
Thioredoxin domain-containing protein.
 
 
  
 0.562
acl-6
Probable glycerol-3-phosphate acyltransferase, mitochondrial; Belongs to the GPAT/DAPAT family.
  
 
 0.505
F37C12.3
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 0.498
Y56A3A.19
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 0.498
acl-7
Dihydroxyacetone phosphate acyltransferase; Belongs to the GPAT/DAPAT family.
  
 
 0.494
chs-1
Chitin synthase chs-1; Essential for the embryonic synthesis of chitin, a component of the eggshell.
  
 
 0.477
pck-2
Phosphoenolypyruvate CarboxyKinase.
      
 0.475
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.