STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Y39G8C.2Protein kinase domain-containing protein. (276 aa)    
Predicted Functional Partners:
tbc-16
Rab-GAP TBC domain-containing protein.
      
 0.917
nep-4
Peptidase_M13 domain-containing protein.
      
 0.895
wdfy-3
WD40 and FYVE domain protein.
   
  
 0.811
daao-1
D-amino-acid oxidase; Catalyzes oxidative deamination of D-amino acids, in particular D-alanine, and could be responsible for the degradation of diet-derived D-alanine in the intestine. Acts on a variety of D-amino acids with greater preference towards those with basic and aromatic groups followed by those bearing neutral groups. Has no activity against acidic D-amino acids, L-amino acids or N-methyl-L-aspartic acid. May play a role in egg-laying events and early development.
 
    
 0.805
agef-1
SEC7 domain-containing protein.
      
 0.741
mgl-2
G_PROTEIN_RECEP_F3_4 domain-containing protein.
      
 0.697
phy-2
Prolyl 4-hydroxylase subunit alpha-2; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins; Belongs to the P4HA family.
      
 0.663
dpy-18
Prolyl 4-hydroxylase subunit alpha-1; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins; Belongs to the P4HA family.
      
 0.463
F21F3.2
Protein kinase domain-containing protein.
  
 
 0.456
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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