Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| F44B9.8 | crn-1 | F44B9.8.1 | Y47G6A.8.1 | Probable replication factor C subunit 5; The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.811 |
| F44B9.8 | hpr-17 | F44B9.8.1 | F32A11.2.2 | Probable replication factor C subunit 5; The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. | Homolog of S. Pombe Rad. | 0.998 |
| F44B9.8 | hpr-9 | F44B9.8.1 | Y39A1A.23a.1 | Probable replication factor C subunit 5; The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. | Cell cycle checkpoint protein hpr-9; May be a component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. | 0.953 |
| F44B9.8 | hus-1 | F44B9.8.1 | H26D21.1.1 | Probable replication factor C subunit 5; The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. | Checkpoint protein. | 0.946 |
| F44B9.8 | mrt-2 | F44B9.8.1 | Y41C4A.14.1 | Probable replication factor C subunit 5; The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. | Cell cycle checkpoint protein RAD1 homolog mrt-2; May be a component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. Promotes DNA double strand break- induced cell cycle arrest and apoptosis, thereby playing a role in genome stability. Also required for telomere length maintenance and germline immortality. May possess 3'->5' double stranded DNA exonuclease activity (By similarity). Belongs to the Rad1 family. | 0.949 |
| F44B9.8 | rad-51 | F44B9.8.1 | Y43C5A.6a.1 | Probable replication factor C subunit 5; The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. | DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. | 0.725 |
| F44B9.8 | rfc-2 | F44B9.8.1 | F58F6.4.1 | Probable replication factor C subunit 5; The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. | AAA domain-containing protein. | 0.999 |
| F44B9.8 | rfc-4 | F44B9.8.1 | F31E3.3.1 | Probable replication factor C subunit 5; The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. | Replication factor C subunit 4; The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins PCNA and activator 1. This subunit may be involved in the elongation of the multiprimed DNA template (By similarity). | 0.999 |
| atm-1 | crn-1 | Y48G1BL.2a.1 | Y47G6A.8.1 | Serine/threonine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling in the presence of DNA double strand breaks (DSBs) and other forms of DNA damage induced by ionizing radiation and other genotoxic stresses such as UV. Plays a role in maintaining genome stability. Belongs to the PI3/PI4-kinase family. ATM subfamily. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.541 |
| atm-1 | hpr-17 | Y48G1BL.2a.1 | F32A11.2.2 | Serine/threonine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling in the presence of DNA double strand breaks (DSBs) and other forms of DNA damage induced by ionizing radiation and other genotoxic stresses such as UV. Plays a role in maintaining genome stability. Belongs to the PI3/PI4-kinase family. ATM subfamily. | Homolog of S. Pombe Rad. | 0.900 |
| atm-1 | hpr-9 | Y48G1BL.2a.1 | Y39A1A.23a.1 | Serine/threonine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling in the presence of DNA double strand breaks (DSBs) and other forms of DNA damage induced by ionizing radiation and other genotoxic stresses such as UV. Plays a role in maintaining genome stability. Belongs to the PI3/PI4-kinase family. ATM subfamily. | Cell cycle checkpoint protein hpr-9; May be a component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. | 0.909 |
| atm-1 | hus-1 | Y48G1BL.2a.1 | H26D21.1.1 | Serine/threonine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling in the presence of DNA double strand breaks (DSBs) and other forms of DNA damage induced by ionizing radiation and other genotoxic stresses such as UV. Plays a role in maintaining genome stability. Belongs to the PI3/PI4-kinase family. ATM subfamily. | Checkpoint protein. | 0.858 |
| atm-1 | lem-3 | Y48G1BL.2a.1 | F42H11.2.1 | Serine/threonine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling in the presence of DNA double strand breaks (DSBs) and other forms of DNA damage induced by ionizing radiation and other genotoxic stresses such as UV. Plays a role in maintaining genome stability. Belongs to the PI3/PI4-kinase family. ATM subfamily. | Ankyrin repeat and LEM domain-containing protein 1 homolog; Endonuclease which, in association with baf-1, plays an essential role during embryogenesis in the DNA repair response following DNA damage probably by ensuring proper chromosome segregation. Also required during postembryonic cell divisions after DNA damage caused by ionizing radiation to ensure normal cell proliferation. Resolves chromatin bridges in late mitosis that result from incomplete DNA replication, defective chromosome condensation or unresolved recombination intermediates. Together with brc-1, contributes to genome [...] | 0.428 |
| atm-1 | mrt-2 | Y48G1BL.2a.1 | Y41C4A.14.1 | Serine/threonine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling in the presence of DNA double strand breaks (DSBs) and other forms of DNA damage induced by ionizing radiation and other genotoxic stresses such as UV. Plays a role in maintaining genome stability. Belongs to the PI3/PI4-kinase family. ATM subfamily. | Cell cycle checkpoint protein RAD1 homolog mrt-2; May be a component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. Promotes DNA double strand break- induced cell cycle arrest and apoptosis, thereby playing a role in genome stability. Also required for telomere length maintenance and germline immortality. May possess 3'->5' double stranded DNA exonuclease activity (By similarity). Belongs to the Rad1 family. | 0.912 |
| atm-1 | rad-51 | Y48G1BL.2a.1 | Y43C5A.6a.1 | Serine/threonine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling in the presence of DNA double strand breaks (DSBs) and other forms of DNA damage induced by ionizing radiation and other genotoxic stresses such as UV. Plays a role in maintaining genome stability. Belongs to the PI3/PI4-kinase family. ATM subfamily. | DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. | 0.926 |
| atm-1 | rfc-2 | Y48G1BL.2a.1 | F58F6.4.1 | Serine/threonine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling in the presence of DNA double strand breaks (DSBs) and other forms of DNA damage induced by ionizing radiation and other genotoxic stresses such as UV. Plays a role in maintaining genome stability. Belongs to the PI3/PI4-kinase family. ATM subfamily. | AAA domain-containing protein. | 0.452 |
| atm-1 | rfc-4 | Y48G1BL.2a.1 | F31E3.3.1 | Serine/threonine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling in the presence of DNA double strand breaks (DSBs) and other forms of DNA damage induced by ionizing radiation and other genotoxic stresses such as UV. Plays a role in maintaining genome stability. Belongs to the PI3/PI4-kinase family. ATM subfamily. | Replication factor C subunit 4; The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins PCNA and activator 1. This subunit may be involved in the elongation of the multiprimed DNA template (By similarity). | 0.462 |
| crn-1 | F44B9.8 | Y47G6A.8.1 | F44B9.8.1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Probable replication factor C subunit 5; The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. | 0.811 |
| crn-1 | atm-1 | Y47G6A.8.1 | Y48G1BL.2a.1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Serine/threonine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling in the presence of DNA double strand breaks (DSBs) and other forms of DNA damage induced by ionizing radiation and other genotoxic stresses such as UV. Plays a role in maintaining genome stability. Belongs to the PI3/PI4-kinase family. ATM subfamily. | 0.541 |
| crn-1 | hpr-17 | Y47G6A.8.1 | F32A11.2.2 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Homolog of S. Pombe Rad. | 0.725 |
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