STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Y41C4A.7Uncharacterized protein. (248 aa)    
Predicted Functional Partners:
F44D12.6
Uncharacterized protein.
   
  
 0.931
R05D7.2
SPK domain-containing protein.
   
  
 0.844
morc-1
Protein morc-1; Involved in gene silencing. Plays a role in germline RNA interference (RNAi), and in particular, the silencing of endogenous small interfering RNA (endo-siRNA) target genes. May play a role in heterochromatin localization and condensation, and the siRNAi-directed trimethylation of 'Lys-9' of histone H3 in hermaphrodite X chromosomes. Promotes transgenerational epigenetic inheritance and germline immortality.
      
 0.809
C18E9.8
Uncharacterized protein.
   
    0.538
rpl-32
Ribosomal Protein, Large subunit.
      
 0.533
C34D4.2
Serine/threonine-protein phosphatase.
   
    0.526
ZK354.6
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
    0.519
alg-4
Putative protein tag-76.
   
  
 0.511
sfxn-1.3
Sidoreflexin.
   
    0.502
R03D7.8
SER_THR_PHOSPHATASE domain-containing protein.
   
    0.487
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.