STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rig-4Protein sidekick homolog; Cell adhesion protein; Belongs to the sidekick family. (2325 aa)    
Predicted Functional Partners:
igcm-3
ImmunoGlobulin-like Cell adhesion Molecule family.
   
 
 0.729
rig-1
NeuRonal IGCAM.
   
  
 0.719
rig-5
Ig-like domain-containing protein.
    
 
 0.705
rig-3
Neuronal immunoglobulin domain-containing protein rig-3; Cell surface protein which plays a role in the plasticity of cholinergic synapses at neuromuscular junctions and in the polarity of the mechanosensory neuron ALM, possibly by antagonizing Wnt signaling.
   
  
 0.695
Y73E7A.3
Uncharacterized protein.
   
  
 0.646
wrk-1
Wrapper/Rega-1/Klingon homolog.
    
 
 0.623
bcc-1
SAM domain-containing protein.
    
 
 0.595
mre-11
Double-strand break repair protein mre-11; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. In response to ionizing radiation, probably required for the association between the brc-1-brd-1 heterodimer and rad-51 and let-70 in order to activate E3-ubiquitin ligase activity of the heterodimer and induce ubiquitination at DNA damage sites. Belongs to the MRE11/RAD32 family.
   
 
 0.576
igcm-1
ImmunoGlobulin-like Cell adhesion Molecule family.
   
 
 0.555
F39B2.8
G_PROTEIN_RECEP_F3_4 domain-containing protein.
      
 0.545
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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