STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Y44A6D.5Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (393 aa)    
Predicted Functional Partners:
bckd-1B
Transket_pyr domain-containing protein.
  
 0.987
bckd-1A
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). Required for the production of the monomethyl branched-chain fatty acids (mmBCFAs) isopentadecanoate (C15iso) and isoheptadecanoate (C17iso).
  
 
 0.977
T09B4.8
Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.942
F54C8.1
Probable 3-hydroxyacyl-CoA dehydrogenase F54C8.1; Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
  
  
 0.935
cth-1
CystaTHionine gamma lyase.
  
 0.929
Y51H7C.9
ACT domain-containing protein.
  
 
 0.929
cth-2
Putative cystathionine gamma-lyase 2; Belongs to the trans-sulfuration enzymes family.
  
 0.929
Y71G12B.10
Pyruvate carboxyltransferase domain-containing protein.
  
 
 0.922
bcat-1
Branched-chain-amino-acid aminotransferase, cytosolic; Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
  
0.907
E01A2.1
Aldo_ket_red domain-containing protein.
  
 
 0.904
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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