STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nhr-110NR LBD domain-containing protein. (424 aa)    
Predicted Functional Partners:
W02A2.8
Uncharacterized protein.
      
 0.854
ZK185.2
Uncharacterized protein.
      
 0.820
F55G11.8
CUB_2 domain-containing protein.
   
  
 0.763
C55A6.7
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
      
 0.758
F13D12.6
Serine carboxypeptidase ctsa-1.2; Belongs to the peptidase S10 family.
   
 
 0.755
scl-2
SCP domain-containing protein; Belongs to the CRISP family.
   
  
 0.713
dhs-2
DeHydrogenases, Short chain; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
      
 0.694
dhps-1
Deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a critical lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. This is the first step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine. Hypusination is unique to mature eIF-5A factor and is essential for its function.
      
 0.694
ZK6.11
Uncharacterized protein.
   
  
 0.677
dod-19
Downstream Of DAF-16 (Regulated by DAF-16).
   
  
 0.674
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.