STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tbx-34Putative T-box protein 34. (302 aa)    
Predicted Functional Partners:
sea-1
T-box transcription factor 18; Probable transcriptional regulator involved in developmental processes. Activates xol-1 transcription, either directly or indirectly, establishing that xol-1 acts as the master regulator to integrate both X chromosome and autosomal signals to determine sexual fate.
  
   
 0.756
mab-9
T-box protein 12; Involved in cell fate determination; required to pattern the posterior hindgut.
  
   
 0.742
twk-39
TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
      
 0.697
mbtr-1
Malignant brain tumor repeat protein 1.
    
 
 0.697
twk-17
Putative potassium channel subunit n2P17m2-2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
      
 0.695
dmsr-3
G_PROTEIN_RECEP_F1_2 domain-containing protein.
      
 0.693
dmsr-6
G_PROTEIN_RECEP_F1_2 domain-containing protein.
      
 0.690
twk-16
TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
      
 0.660
F32B6.4
Uncharacterized protein.
   
    0.615
ZK1248.5
DUF1248 domain-containing protein.
   
    0.613
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.