STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Y47G6A.15Uncharacterized protein. (278 aa)    
Predicted Functional Partners:
cand-1
Cullin-associated NEDD8-dissociated protein 1; Key assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate- recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes. Acts as a F-box protein exchange factor (Probable).
      
 0.620
col-175
Col_cuticle_N domain-containing protein.
   
    0.513
col-138
Col_cuticle_N domain-containing protein.
   
    0.455
bli-1
Cuticle collagen bli-1; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment. This collagen is required for proper strut formation within the unique medial layer of the adult cuticle.
   
    0.439
Y51H7C.13
Uncharacterized protein.
   
    0.434
col-71
Col_cuticle_N domain-containing protein.
   
    0.422
rol-1
Col_cuticle_N domain-containing protein.
   
    0.420
bli-2
Col_cuticle_N domain-containing protein.
   
    0.416
col-49
Col_cuticle_N domain-containing protein.
   
    0.412
E01G4.6
Uncharacterized protein.
   
    0.403
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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